@article{3097210, title = "Out-patient management of chronic heart failure", author = "Terrovitis, JV and Anastasiou-Nana, MI and Nanas, JN", journal = "Expert Opinion on Pharmacotherapy", year = "2005", volume = "6", number = "11", pages = "1857-1881", publisher = "TAYLOR & FRANCIS LTD LONDON", issn = "1465-6566, 1744-7666", doi = "10.1517/14656566.6.11.1857", keywords = "aldosterone antagonism; ambulatory medicine; angiotensin-converting enzyme inhibition; beta-adrenergic blockade; drug therapy; heart failure", abstract = "Chronic heart failure is a clinical syndrome associated with an ominous long-term prognosis and major economic consequences for Western societies. In recent years, considerable progress has been made in the pharmacological management of heart failure, and several treatments have been confirmed to confer survival and symptomatic benefits. However, pharmaceuticals remain underutilised, and the combination of several different drugs present challenges for their optimal prescription, requiring a thorough knowledge of potential side effects and complex interactions. This article reviews in detail the evidence pertaining to the out-patient pharmacological management of chronic heart failure, and offers recommendations on the use of various drugs in complex clinical conditions, or in areas of ongoing controversy." }