@article{3100604, title = "Advancing the global public health agenda for NAFLD: a consensus statement", author = "Lazarus, J.V. and Mark, H.E. and Anstee, Q.M. and Arab, J.P. and Batterham, R.L. and Castera, L. and Cortez-Pinto, H. and Crespo, J. and Cusi, K. and Dirac, M.A. and Francque, S. and George, J. and Hagström, H. and Huang, T.T.-K. and Ismail, M.H. and Kautz, A. and Sarin, S.K. and Loomba, R. and Miller, V. and Newsome, P.N. and Ninburg, M. and Ocama, P. and Ratziu, V. and Rinella, M. and Romero, D. and Romero-Gómez, M. and Schattenberg, J.M. and Tsochatzis, E.A. and Valenti, L. and Wong, V.W.-S. and Yilmaz, Y. and Younossi, Z.M. and Zelber-Sagi, S. and Åberg, F. and Adams, L. and Khatry, M.S.A. and Naamani, K.A. and Murillo, O.A. and Allen, A.M. and Alnaser, F. and Alqahtani, S.A. and Alswat, K. and Alvaro, D. and Andrade, R.J. and Arrese, M. and Awuku, Y.A. and Ayesha, M. and Baatarkhuu, O. and Bakieva, S. and Basu, R. and Bataller, R. and Bedri, S. and Bosi, E. and Bourliere, M. and Bruha, R. and Bugianesi, E. and Burra, P. and Buti, M. and Byrne, C.D. and Calleja, J.L. and Carrieri, P. and Carter, F. and Fernandez, M.I.C. and Castillo-Lopez, G. and Castro-Narro, G.E. and Chan, H.L.Y. and Chan, W.-K. and Chang, Y. and Colombo, M. and Coppell, K.J. and Corey, K. and Craxi, A. and Cryer, D. and Dassanayake, A. and Martins, A.A.S. and de Ledinghen, V. and DelPrato, S. and Demaio, A. and Desalegn, H. and Dillon, J. and Duseja, A. and Dorairaj, P. and Ekstedt, M. and El Kassas, M. and Elsanousi, O.M. and Esmat, G. and Fan, J.-G. and Farpour-Lambert, N. and Flisiak, R. and Fouad, Y. and Fuchs, M. and Gani, R.A. and Gerber, L. and Ghazinyan, H. and Gheorghe, L. and Goh, G.B.-B. and Grønbæk, H. and Gulnara, A. and Hamid, S. and Hebditch, V. and Hickman, I.J. and Hocking, S.L. and Hunyady, B. and Idilman, R. and Isakov, V.A. and Jamal, M.H. and Jepsen, P. and Iskandar, N.J. and Song, M.J. and Sudhamshu, K.C. and Kakizaki, S. and Kalamitsis, G. and Kanwal, F. and Kao, J.-H. and Kaplan, L. and Kawaguchi, T. and Khader, Y. and Kim, S.U. and Kodjoh, N. and Koek, G. and Koike, K. and Komas, N.P. and Korenjak, M. and Kugelmas, M. and Labidi, A. and Lange, N.F. and Lavine, J.E. and Lazo, M. and Lee, N. and Lesmana, C.R.A. and Liu, C.-J. and Long, M.T. and Lopez-Jaramillo, P. and Malekzadeh, R. and Mahtab, M.A. and Marchesini, G. and Marinho, R. and Vázquez, S.E.M. and Mateva, L. and Nlombi, C.M. and Melin, P. and Mikolasevic, I. and Milovanovic, T. and Musso, C. and Nakajima, A. and Nava, E. and Nersesov, A.V. and Nikolova, D. and Norris, S. and Novak, K. and Oben, J. and Ong, J.P. and Onyekwere, C. and Papatheodoridis, G. and Paruk, I. and Patel, K. and Macedo, M.P. and Penha-Gonçalves, C. and Figueroa, M.P. and Hofmann, W.P. and Petta, S. and de Oliveira, C.P.M.S. and Puri, P. and Pan, C.Q. and Rac, M. and Ralston, J. and Ramji, A. and Razavi, H. and Alvares-da-Silva, M.R. and Roberts, S. and Roden, M. and Rose, T. and Rouabhia, S. and Rovere-Querini, P. and Rowe, I.A. and Sadirova, S. and Salupere, R. and Saparbu, T. and Sayegh, R. and Sebastiani, G. and Seki, Y. and Selmo, J. and Serme, A.K. and Shaw, J.E. and Shenoy, T. and Sheron, N. and Shibolet, O. and Silva, M. and Skrypnyk, I. and Socha, P. and Soriano, J. and Spearman, C.W. and Sridharan, K. and Suárez, J.J. and Sheriff, D.S. and Sung, K.-C. and Swain, M. and Tacke, F. and Taheri, S. and Tan, S.-S. and Tapper, E.B. and Yki-Järvinen, H. and Thiele, M. and Shawa, I.T. and Tolmane, I. and Torres, E.A. and Trauner, M. and Treeprasertsuk, S. and Turcanu, A. and Valantinas, J. and Vesterhus, M. and Waked, I. and Wild, S.H. and Willemse, J. and Wong, R.J. and Xanthakos, S. and Young, D.Y. and Yu, M.-L. and Zheng, K.I. and Zeybel, M. and Zheng, M.-H. and the NAFLD Consensus Consortium", journal = "Nature Reviews Gastroenterology and Hepatology", year = "2022", volume = "19", number = "1", pages = "60-78", publisher = "Lithuanian Nature Research Centre", doi = "10.1038/s41575-021-00523-4", keywords = "human; nonalcoholic fatty liver, Humans; Non-alcoholic Fatty Liver Disease", abstract = "Non-alcoholic fatty liver disease (NAFLD) is a potentially serious liver disease that affects approximately one-quarter of the global adult population, causing a substantial burden of ill health with wide-ranging social and economic implications. It is a multisystem disease and is considered the hepatic component of metabolic syndrome. Unlike other highly prevalent conditions, NAFLD has received little attention from the global public health community. Health system and public health responses to NAFLD have been weak and fragmented, and, despite its pervasiveness, NAFLD is largely unknown outside hepatology and gastroenterology. There is only a nascent global public health movement addressing NAFLD, and the disease is absent from nearly all national and international strategies and policies for non-communicable diseases, including obesity. In this global Delphi study, a multidisciplinary group of experts developed consensus statements and recommendations, which a larger group of collaborators reviewed over three rounds until consensus was achieved. The resulting consensus statements and recommendations address a broad range of topics — from epidemiology, awareness, care and treatment to public health policies and leadership — that have general relevance for policy-makers, health-care practitioners, civil society groups, research institutions and affected populations. These recommendations should provide a strong foundation for a comprehensive public health response to NAFLD. © 2021, Springer Nature Limited." }