@article{3103116,
    title = "Anesthetic management of a patient with charcot-marie-tooth disease for 2-stage revision of total knee replacement",
    author = "Soulioti, E. and Kavezou, F. and Efstathiou, G. and Batistaki, C. and Karakosta, A. and Kostopanagiotou, G.",
    journal = "Turkish Journal of Anaesthesiology and Reanimation",
    year = "2021",
    volume = "49",
    number = "2",
    pages = "178-180",
    publisher = "AVES Publishing Co.",
    doi = "10.5152/TJAR.2021.513",
    abstract = "Charcot-Marie-Tooth disease is characterised by hereditary motor and sensory neuropathy. Its anaesthetic management is challenging owing to the unpredictable response observed in patients, especially to non-depolarising neuromuscular blocking drugs, and the risk of malignant hyperthermia and cardiorespiratory complications. A 66-year-old woman underwent anaesthesia for 2 different surgical pro-cedures, a 2-stage revision of total knee replacement over a 4-month period. She presented with severe anatomic disorders, accompanied by severe motor and sensory impairment. An anaesthetic plan without neuromuscular blocking drugs or volatile anaesthetics, using a clean ventilator, with dantrolene available, was successfully used both times. There were no complications during the administration of general anaesthesia or postoperatively at the post-anaesthesia care unit, and the patient did not complain of pain at any time. General anaesthesia with a careful selection of anaesthetic drugs proved to be a safe option for the management of a patient with Charcot-Ma-rie-Tooth disease. © 2021 by Turkish Society of Anaesthesiology and Reanimation-Available online at www.jtaics.org."
}