@article{3104306, title = "Is TKA with computer-assisted navigation associated with less blood loss? A comparative study between computer-navigated and conventional method", author = "Mitsiou, D. and Pakos, E.E. and Papadopoulos, D.V. and Georgiadis, G. and Gelalis, I.D. and Tsantes, A.G. and Gkiatas, I. and Kalos, N. and Xenakis, T.A.", journal = "Indian Journal of Orthopaedics", year = "2020", volume = "20", pages = "50-53", publisher = "Reed Elsevier India Pvt. Ltd.", doi = "10.1016/j.jor.2020.01.014", keywords = "hemoglobin, adult; aged; Article; blood transfusion; comparative effectiveness; computer assisted surgery; controlled study; female; hematocrit; human; intermethod comparison; major clinical study; male; operative blood loss; priority journal; prospective study; randomized controlled trial; total knee arthroplasty", abstract = "The aim of this study is to evaluate whether computer-assisted navigated TKA reduces perioperative blood loss. Patients were randomly divided into 2 groups and underwent either a conventional TKA (n = 40) or a TKA with computer-assisted navigation (n = 40). Perioperative blood loss was evaluated by laboratory parameters, postoperative drain output and number of required transfusions. Change in hemoglobin concentration and in hematocrit levels was similar. Also, there was no statistically significant difference in drain output and in the number of transfused units. The results of this study showed that TKA with computer-assisted navigation is similar to the conventional TKA regarding perioperative hemorrhage. © 2020 Professor P K Surendran Memorial Education Foundation" }