@article{3105225,
    title = "Multifocal and multicentric breast cancer, is it time to think again?",
    author = "Masannat, Y.A. and Agrawal, A. and Maraqa, L. and Fuller, M. and Down, S.K. and Tang, S.S.K. and Pang, D. and Kontos, M. and Romics, L. and Heys, S.D.",
    journal = "Annals of the Royal College of Surgeons of England",
    year = "2020",
    volume = "102",
    number = "1",
    pages = "62-66",
    publisher = "Royal College of Surgeons of England",
    issn = "0035-8843, 1478-7083",
    doi = "10.1308/rcsann.2019.0109",
    keywords = "breast tumor;  clinical decision making;  clinical practice;  epidemiology;  feasibility study;  female;  human;  mastectomy;  meta analysis;  mortality;  partial mastectomy;  procedures;  treatment outcome, Breast Neoplasms;  Clinical Decision-Making;  Epidemiologic Methods;  Feasibility Studies;  Female;  Humans;  Mastectomy;  Mastectomy, Segmental;  Practice Patterns, Physicians';  Treatment Outcome",
    abstract = "Multifocal multicentric breast cancer has traditionally been considered a contraindication to breast conserving surgery because of concerns regarding locoregional control and risk of disease recurrence. However, the evidence supporting this practice is limited. Increasingly, many breast surgeons are advocating breast conservation in selected cases. This short narrative review summarises current evidence on the role of surgery in multifocal multicentric breast cancer and shows that when technically feasible the option of breast conservation is oncologically safe. © 2020 Royal College of Surgeons of England. All rights reserved."
}