@article{3106932,
    title = "Echocardiography for the management of patients with biventricular pacing: Possible roles in cardiac resynchronization therapy implementation",
    author = "Poulidakis, E. and Aggeli, C. and Kappos, K. and Manolis, A.S. and Sideris, S. and Gatzoulis, K. and Oikonomou, E. and Tousoulis, D.",
    journal = "Ελληνική καρδιολογική επιθεώρηση",
    year = "2018",
    volume = "59",
    number = "6",
    pages = "306-312",
    publisher = "Hellenic Cardiological Society",
    issn = "1011-7970",
    doi = "10.1016/j.hjc.2018.02.006",
    keywords = "aortic valve;  cardiac resynchronization therapy;  dyssynchrony index;  echocardiography;  follow up;  heart ejection fraction;  heart failure;  heart failure with reduced ejection fraction;  heart left bundle branch block;  heart left ventricle;  heart left ventricle volume;  human;  inotropic contractile reserve;  interventricular septum;  isovolumic time;  left ventricular pre ejection interval;  M mode echocardiography;  mitral valve;  nonhuman;  QRS interval;  Review;  sensitivity and specificity;  speckle tracking echocardiography;  systolic stretch index;  tissue Doppler imaging;  cardiac resynchronization therapy;  diagnostic imaging;  echocardiography;  electrocardiography;  heart left ventricle function;  heart stroke volume;  heart ventricle;  pathophysiology;  physiology;  procedures;  treatment outcome, Cardiac Resynchronization Therapy;  Echocardiography;  Electrocardiography;  Heart Failure;  Heart Ventricles;  Humans;  Stroke Volume;  Treatment Outcome;  Ventricular Function, Left",
    abstract = "Cardiac resynchronization therapy (CRT) is an established therapeutic option for the subset of patients with heart failure (HF), reduced ejection fraction (EF), and dyssynchrony evidenced by electrocardiography. Benefit from CRT has been proven in many clinical trials, yet a sizeable proportion of these patients with wide QRS do not respond to this intervention, despite the updated practice guidelines. Several echocardiographic indices, targeting mechanical rather than electrical dyssynchrony, have been suggested to address this issue, but research so far has not succeeded in providing a single and simple measurement with adequate sensitivity and specificity for identification of responders. While there is still ongoing research in this field, echocardiography proves helpful in other aspects of CRT implementation, such as site selection for left ventricular (LV) lead pacing and optimization of pacing parameters during follow-up visits. © 2018 Hellenic Society of Cardiology"
}