@article{3107068,
    title = "Current concepts for the evaluation and management of diabetic foot ulcers",
    author = "Mavrogenis, A.F. and Megaloikonomos, P.D. and Antoniadou, T. and Igoumenou, V.G. and Panagopoulos, G.N. and Dimopoulos, L. and Moulakakis, K.G. and Sfyroeras, G.S. and Lazaris, A.",
    journal = "EFORT Open Reviews",
    year = "2018",
    volume = "3",
    number = "9",
    pages = "513-525",
    publisher = "British Editorial Society of Bone and Joint Surgery",
    issn = "2396-7544, 2058-5241",
    doi = "10.1302/2058-5241.3.180010",
    keywords = "antibiotic agent, awareness;  blood glucose monitoring;  clinical evaluation;  clinical outcome;  debridement;  diabetic foot;  disease control;  disease severity;  foot amputation;  foot care;  high risk patient;  human;  infection control;  ischemia;  mortality;  osteomyelitis;  pathophysiology;  revascularization;  Review;  risk assessment;  skin ulcer;  weight bearing;  wound care;  wound infection",
    abstract = "The lifetime risk for diabetic patients to develop a diabetic foot ulcer (DFU) is 25%. In these patients, the risk of amputation is increased and the outcome deteriorates. More than 50% of non-traumatic lower-extremity amputations are related to DFU infections and 85% of all lowerextremity amputations in patients with diabetes are preceded by an ulcer; up to 70% of diabetic patients with a DFU-related amputation die within five years of their amputation. Optimal management of patients with DFUs must include clinical awareness, adequate blood glucose control, periodic foot inspection, custom therapeutic footwear, offloading in high-risk patients, local wound care, diagnosis and control of osteomyelitis and ischaemia. © 2018 The author(s)."
}