@article{3107180, title = "The Micro-Elimination Approach to Eliminating Hepatitis C: Strategic and Operational Considerations", author = "Lazarus, J.V. and Safreed-Harmon, K. and Thursz, M.R. and Dillon, J.F. and El-Sayed, M.H. and Elsharkawy, A.M. and Hatzakis, A. and Jadoul, M. and Prestileo, T. and Razavi, H. and Rockstroh, J.K. and Wiktor, S.Z. and Colombo, M.", journal = "Seminars in Liver Disease", year = "2018", volume = "38", number = "3", pages = "181-192", publisher = "Thieme Medical Publishers Inc", issn = "0272-8087, 1098-8971", doi = "10.1055/s-0038-1666841", keywords = "disease elimination; graft recipient; hematologic disease; hemodialysis patient; hemophilia; hepatitis C; high risk population; human; Human immunodeficiency virus infection; indigenous people; migrant; mixed infection; people who inject drug; prevalence; priority journal; prisoner; Review; cooperation; disease eradication; ethnology; global health; health care policy; hepatitis C; integrated health care system; interdisciplinary communication; international cooperation; legislation and jurisprudence; management; nonbiological model; organization and management; risk factor; stakeholder engagement; transmission; vulnerable population, antivirus agent, Antiviral Agents; Cooperative Behavior; Delivery of Health Care, Integrated; Disease Eradication; Global Health; Health Policy; Hepatitis C; Humans; Interdisciplinary Communication; International Cooperation; Models, Organizational; Policy Making; Prevalence; Risk Factors; Stakeholder Participation; Vulnerable Populations", abstract = "The introduction of efficacious new hepatitis C virus (HCV) treatments galvanized the World Health Organization to define ambitious targets for eliminating HCV as a public health threat by 2030. Formidable obstacles to reaching this goal can best be overcome through a micro-elimination approach, which entails pursuing elimination goals in discrete populations through multi-stakeholder initiatives that tailor interventions to the needs of these populations. Micro-elimination is less daunting, less complex, and less costly than full-scale, country-level initiatives to eliminate HCV, and it can build momentum by producing small victories that inspire more ambitious efforts. The micro-elimination approach encourages stakeholders who are most knowledgeable about specific populations to engage with each other and also promotes the uptake of new models of care. Examples of micro-elimination target populations include medical patients, people who inject drugs, migrants, and prisoners, although candidate populations can be expected to vary greatly in different countries and subnational areas. © 2018 by Thieme Medical Publishers, Inc." }