@article{3107906,
    title = "Patient-and Caregiver-Related Factors Associated with Caregiver Assessed Global Deterioration Scale Scoring in Demented Patients",
    author = "Mougias, A.A. and Christidi, F. and Kontogianni, E. and Skaltsounaki, E. and Politis, A. and Politis, A.",
    journal = "Current Gerontology and Geriatrics Research",
    year = "2018",
    volume = "2018",
    publisher = "Hindawi Limited",
    issn = "1687-7063, 1687-7071",
    doi = "10.1155/2018/9396160",
    abstract = "Background. Informant-based rating scales are widely used in dementia but patients' and caregivers' features influence the final scoring. We aimed to evaluate the role of patient-and caregiver-related factors in a caregiver rated Global Deterioration Scale (GDS) score in a sample of Greek patients with dementia. Methods. We included 194 patients with dementia and 194 caregivers/family relatives; Mini-Mental State Examination (MMSE); Neuropsychiatric Inventory (NPI); Katz Index of Activities of Daily Living (K-IADL) were administered to (a) patients and Center for Epidemiologic Studies-Depression (CES-D) Scale; Zarit Burden Interview (ZBI) to (b) caregivers. Participants' demographics and patients' and caregivers' characteristics were entered into a 3-block regression analysis. Results. The final model explained 55% of the total variance of the caregiver assessed GDS score. The following variables significantly contributed to the final model: MMSE (β=-0.524); K-IADL (β=-0.264); ZBI (β=0.145). Conclusion. We herein confirm the contribution of patients' cognitive and functional status and caregivers' burden in caregiver rated GDS scoring irrespective of demographic-related characteristics. © 2018 Antonios A. Mougias et al."
}