@article{3109144,
    title = "Treatment of severe hypocalcaemia due to osteoblastic metastases in a patient with post-thyroidectomy hypoparathyroidism with 153 Sm-EDTMP",
    author = "Kassi, E. and Kapsali, I. and Kokkinos, M. and Gogas, H.",
    journal = "BMJ Case Reports",
    year = "2017",
    volume = "2017",
    publisher = "BMJ Publishing Group",
    issn = "1757-790x",
    doi = "10.1136/bcr-2017-219354",
    keywords = "alfacalcidol;  calcium;  calcium carbonate;  carboplatin;  citrate calcium;  colecalciferol;  levothyroxine;  lexidronam samarium sm 153;  magnesium;  paclitaxel;  zoledronic acid;  analgesic agent;  calcium;  organometallic compound;  organophosphorus compound;  radioisotope;  samarium Sm-153 lexidronam, aged;  anamnesis;  Article;  bone metastasis;  breast cancer;  calcium blood level;  cancer combination chemotherapy;  cancer hormone therapy;  cancer radiotherapy;  case report;  computer assisted tomography;  differential diagnosis;  dose response;  drug dose reduction;  female;  hormone substitution;  hospital discharge;  human;  hypocalcemia;  hypoparathyroidism;  hypothyroidism;  liver metastasis;  postoperative complication;  priority journal;  simple mastectomy;  spleen metastasis;  thyroidectomy;  toxic goiter;  treatment duration;  blood;  bone tumor;  breast tumor;  complication;  hypocalcemia;  hypoparathyroidism;  intravenous drug administration;  osteoblast;  pathology;  postoperative complication;  secondary;  thyroidectomy;  treatment outcome, Administration, Intravenous;  Aged;  Analgesics, Non-Narcotic;  Bone Neoplasms;  Breast Neoplasms;  Calcium;  Diagnosis, Differential;  Female;  Humans;  Hypocalcemia;  Hypoparathyroidism;  Organometallic Compounds;  Organophosphorus Compounds;  Osteoblasts;  Postoperative Complications;  Radioisotopes;  Thyroidectomy;  Treatment Outcome",
    abstract = "Symptomatic hypocalcaemia is an uncommon finding in patients with malignant tumours. We describe a patient with advanced metastatic breast cancer who developed severe hypocalcaemia caused by the combination of osteoblastic metastases and a permanent postoperative hypoparathyroidism. The patient failed to be treated with the conventional replacement therapy and was submitted effectively to radionucleotide therapy with 153 Sm. © BMJ Publishing Group Ltd (unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted."
}