@article{3109783, title = "Symptoms associated with button batteries injuries in children: An epidemiological review", author = "Buttazzoni, E. and Gregori, D. and Paoli, B. and Soriani, N. and Baldas, S. and Rodriguez, H. and Lorenzoni, G. and Marquez, C.R. and Cuestas, G. and Sica, G. and Berchialla, P. and Zaupa, P. and Spitzer, P. and Demetriades, C. and Ŝlapák, I. and Sokolova, L. and Petridou, E. and Antonio, M. and Jakubíková, J. and As, S.V. and Koning, T.D. and Passali, D. and Bouchikhi, N. and Boufersaoui, A. and Chinsky, A. and Tortosa, S. and Blasio, A.D. and Rodríguez, V. and Taire, D. and Razetti, J. and Mariotti, C.A. and Ariel, A.H. and Zanetta, A. and Dario, F. and Pabón, S.M. and Quijano, A. and Nieto, M.E. and Bordino, L. and Dallakyan, N. and Dallakyan, D. and Villca, N. and Brkic, F. and Umihanic, S. and Reis, M. and Manrique, D. and Nkodo, Y. and Ludemann, J. and Chengpeng, J. and Puentes, O.U.B. and Mladina, R. and De La Rosa, E.G. and Kalakouta, O. and Melis, A. and Zeitouni, F. and Máchalová, M. and Slapak, J. and Pecková, P. and Caye-Thomasen, P. and Chacon, F.S. and Parker, J. and Elsheikh, E. and Ragab, A. and Pitkäranta, A. and Necker, P.C. and Derelle, J. and Duwelz, M. and Francois, M. and Pezzettigotta, S. and Righini, C. and Chkhaidze, I. and Bernhard, R. and Jahnke, V. and Onder, G. and Zieriacks, P. and Siegfried, K. and Koitschev, A. and Kalampoki, V. and Simasko, N. and Skoulakis, C. and Gulati, A. and Nimbalkar, S. and Sharma, Y. and Squicciarini, M. and Damasco, M. and Camaioni, A. and Cutrone, C. and Gaudini, E. and Grassom, D. and Messi, G. and Mansi, N. and Orlando, C. and Preziosi, S. and Sorrentini, I. and Villari, G. and Trozzi, M. and Vigo, A. and Passali, G.C. and Passali, F.M. and Piantanida, R. and Giordano, C. and Mercuri, L. and Cecconi, A. and Giovari, M. and Calderini, E. and Nishida, Y. and Saito, T. and Ussatayeva, G. and De Hoyos Parra, R.A. and Treviño Gonzalez, J.L. and Ramayo, S. and Ologe, F.E. and Afolabi, O. and Nasrullah, M. and Melendez, A. and Milanes, R. and Chmielik, M. and Belchior, T. and Cobzeanu, M.D. and Gheorghe, D.C. and Iorgulescu, A. and Toader, M. and Codrut, C. and Stankovic, K. and Barkociová, J. and Havelkova, B. and Jakubikova, J. and Koman, A. and Zargi, M. and Pumarola, F. and Rubio, L. and Peco, K.P. and Stierna, P. and Hsu, W.-C. and Arj-Ong, S. and Chomchai, C. and Chotigavanich, C. and Hoep, L. and Rinkel, R. and Berraies, A. and Baskent, E.A. and Erikci, V.S. and Onerci, M. and Graham, J. and Khwaja, S. and Raine, C. and Haloob, N. and Haedo, I.D.G. and Mehta, D. and Casselbrant, M. and Toan, P.N. and The Susy Safe Working Group", journal = "International Journal of Pediatric Otorhinolaryngology", year = "2015", volume = "79", number = "12", pages = "2200-2207", publisher = "Elsevier Ireland Ltd", issn = "0165-5876", doi = "10.1016/j.ijporl.2015.10.003", keywords = "abdominal pain; adult; anorexia; Article; bronchoscopy; bronchus perforation; child; controlled study; coughing; crying; dysphagia; dysphonia; ear foreign body; eardrum perforation; electric battery; endoscopy; epistaxis; esophagogastroduodenoscopy; esophagus fistula; esophagus foreign body; esophagus perforation; esophagus ulcer; female; fever; foreign body; human; hypersalivation; infant; irritability; laryngoscopy; larynx foreign body; lethargy; lung foreign body; major clinical study; male; melena; mouth foreign body; mouth ulcer; nose foreign body; nose septum perforation; nose ulcer; oral fistula; otoscopy; pharynx foreign body; prevalence; priority journal; rhinorrhea; stomach foreign body; stomach perforation; symptom; thorax pain; trachea foreign body; adolescent; complication; Cough; Deglutition Disorders; eating; esophagus; factual database; fever; Foreign Bodies; inhalation; injuries; mouth; newborn; nose cavity; power supply; preschool child; register; Sialorrhea; stomach; symptom assessment, Adolescent; Child; Child, Preschool; Cough; Crying; Databases, Factual; Deglutition Disorders; Eating; Electric Power Supplies; Epidemiologic Studies; Esophagus; Female; Fever; Foreign Bodies; Humans; Infant; Infant, Newborn; Inhalation; Male; Mouth; Nasal Cavity; Registries; Sialorrhea; Stomach; Symptom Assessment", abstract = "Objectives: To provide an epidemiological framework of symptoms related to Foreign Body (FB) injuries due to Button Battery (BB). Methods: Data on BB ingestion/inhalation have been obtained from the ButtonBatteryDB. The ButtonBatteryDB is a database collecting information on BB injuries in children (0-18 years of age). Data on 348 BB injures have been derived from the Registry of Foreign Body Injuries "Susy Safe" (269 cases) and from published scientific literature reporting case reports of FB injuries (79 cases). Results: Most of injured children were male and BBs were found more often in the mouth/esophagus/stomach (ICD935) and in the nose (ICD932). Analyzing symptoms related to BB located in the esophagus/mouth/stomach, we found that children had higher probability of experiencing dysphagia (30.19%, 95% C.I. 17.83-42.55), fever and cough (26.42%, 95% C.I. 14.55-38.28), compared to the other symptoms. Referring to the probability that symptoms occurred simultaneously, fever and cough are more likely (3.72%, 95% C.I. 1.0-6-43) to jointly showing up in children with BB in mouth/esophagus/stomach (ICD935), followed by fever and dysphagia (2.66%, 95% C.I. 0.36-4.96) and by fever and irritability/crying, fever and drooling, dysphagia and irritability/crying (2.13% C.I. 0.00-4.19, 95% C.I.). Conclusions: These findings provide new insight in clinical presentation of BB injuries: the identification of unique patterns of symptoms related to BB injuries is useful to perform an early diagnosis (and to guarantee a prompt medical reaction), also when the injury is un-witnessed. © 2015 Elsevier Ireland Ltd." }