@article{3111274, title = "ESCMID guideline for the diagnosis and management of Candida diseases 2012: Diagnostic procedures", author = "Cuenca-Estrella, M. and Verweij, P.E. and Arendrup, M.C. and Arikan-Akdagli, S. and Bille, J. and Donnelly, J.P. and Jensen, H.E. and Lass-Flörl, C. and Richardson, M.D. and Akova, M. and Bassetti, M. and Calandra, T. and Castagnola, E. and Cornely, O.A. and Garbino, J. and Groll, A.H. and Herbrecht, R. and Hope, W.W. and Kullberg, B.J. and Lortholary, O. and Meersseman, W. and Petrikkos, G. and Roilides, E. and Viscoli, C. and Ullmann, A.J.", journal = "Clinical Microbiology and Infection", year = "2012", volume = "18", number = "SUPPL.7", pages = "9-18", publisher = "Wiley-Blackwell Publishing Ltd", issn = "1198-743X", doi = "10.1111/1469-0691.12038", keywords = "amphotericin B; anidulafungin; beta 1,3 glucan; caspofungin; fluconazole; flucytosine; itraconazole; micafungin; posaconazole; voriconazole; antifungal agent; biological marker, antifungal susceptibility; article; blood culture; candidemia; candidiasis; diagnostic accuracy; diagnostic procedure; drug monitoring; esophagitis; esophagus candidiasis; extracorporeal oxygenation; histopathology; human; invasive candidiasis; meta analysis (topic); microscopy; neutropenia; nonhuman; oropharynx candidiasis; polymerase chain reaction; practice guideline; priority journal; sensitivity and specificity; vagina candidiasis; vaginal secretion; Candida; drug effect; evidence based medicine; isolation and purification; microbial sensitivity test; practice guideline, Antifungal Agents; Biological Markers; Candida; Candidiasis; Evidence-Based Medicine; Humans; Microbial Sensitivity Tests", abstract = "As the mortality associated with invasive Candida infections remains high, it is important to make optimal use of available diagnostic tools to initiate antifungal therapy as early as possible and to select the most appropriate antifungal drug. A panel of experts of the European Fungal Infection Study Group (EFISG) of the European Society of Clinical Microbiology and Infectious Diseases (ESCMID) undertook a data review and compiled guidelines for the clinical utility and accuracy of different diagnostic tests and procedures for detection of Candida infections. Recommendations about the microbiological investigation and detection of candidaemia, invasive candidiasis, chronic disseminated candidiasis, and oropharyngeal, oesophageal, and vaginal candidiasis were included. In addition, remarks about antifungal susceptibility testing and therapeutic drug monitoring were made. © 2012 The Authors. Clinical Microbiology and Infection © 2012 European Society of Clinical Microbiology and Infectious Diseases." }