@article{3111818,
    title = "Occupation and risk of lymphoma: A multicentre prospective cohort study (EPIC)",
    author = "Neasham, D. and Sifi, A. and Nielsen, K.R. and Overvad, K. and Raaschou-Nielsen, O. and Tjønneland, A. and Barricarte, A. and González, C.A. and Navarro, C. and Suarez, L.R. and Travis, R.C. and Key, T. and Linseisen, J. and Kaaks, R. and Crosignani, P. and Berrino, F. and Rosso, S. and Mattiello, A. and Vermeulen, R.C.H. and Bueno-de-Mesquita, H.B. and Berglund, G. and Manjer, J. and Zackrisson, S. and Hallmans, G. and Malmer, B. and Bingham, S. and Khaw, K.T. and Bergmann, M.M. and Boeing, H. and Trichopoulou, A. and Masala, G. and Tumino, R. and Lund, E. and Slimani, N. and Ferrari, P. and Boffetta, P. and Vineis, P. and Riboli, E.",
    journal = "Annals of Occupational and Environmental Medicine",
    year = "2011",
    volume = "68",
    number = "1",
    pages = "77-81",
    issn = "2052-4374",
    doi = "10.1136/oem.2009.048173",
    keywords = "gasoline;  solvent, adult;  aged;  article;  cancer risk;  cohort analysis;  Europe;  female;  follow up;  high risk population;  Hodgkin disease;  human;  major clinical study;  male;  multicenter study (topic);  multiple myeloma;  nonhodgkin lymphoma;  occupational cancer;  occupational exposure;  occupational hazard;  plasmacytoma;  priority journal;  prospective study;  risk factor;  zoonosis, Adult;  Age Distribution;  Aged;  Epidemiologic Methods;  Europe;  Female;  Humans;  Lymphoma;  Lymphoma, Non-Hodgkin;  Male;  Middle Aged;  Occupational Diseases;  Occupational Exposure;  Occupations",
    abstract = "Objectives: Evidence suggests that certain occupations and related exposures may increase the risk of malignant lymphoma. Farming, printing and paper industry, wood processing, meat handling and processing, welding, shoe and leather manufacturing and teaching profession are among the categories that have been implicated in previous studies. The relationship between occupation and malignant lymphoma has been investigated in a large European prospective study. Methods: We investigated occupational risks for lymphomas in the European Prospective Investigation into Cancer and Nutrition (EPIC). The mean follow-up time for 348 555 subjects was 9 years (SD: 2 years). The analysis was based on 866 and 48 newly diagnosed cases of non-Hodgkin's lymphoma (NHL) and Hodgkin's lymphoma (HL). These were identified in the EPIC subcohorts with occupational data. Data on 52 occupations were collected through standardised questionnaires. Cox proportional hazard models were used to explore the association between occupation and risk of malignant lymphoma. Results: The following occupations were positively associated with malignant NHL after adjustment for study centre, age, sex, socioeconomic status (SES), smoking and alcohol: butchers (HR=1.53, 95% CI 1.05 to 2.48, including multiple myeloma/plasmacytoma; HR=1.30, 95% CI 1.00 to 2.66, excluding multiple myeloma/plasmacytoma) and car repair workers (HR=1.50, 95% CI 1.01 to 2.00, including multiple myeloma/plasmacytoma; HR=1.51, 95% CI 1.01 to 2.31, excluding multiple myeloma/plasmacytoma). HL was associated with gasoline station occupation (HR=4.59, 95% CI 1.08 to 19.6). Conclusion: The findings in this current study of a higher risk of NHL among car repair workers and butchers and a higher risk of HL among gasoline station workers suggest a possible role from occupationally related exposures, such as solvents and zoonotic viruses, as risk factors for malignant lymphoma."
}