@article{3114705, title = "Acute necrotizing encephalopathy of childhood in non-Asian patients: Report of three cases and literature review", author = "Mastroyianni, Sotiria D. and Gionnis, Dimitrios and Voudris, and Konstantinos and Skardoutsou, Angeliki and Mizuguchi, Masashi", journal = "Journal of Child Neurology", year = "2006", volume = "21", number = "10", pages = "872-879", publisher = "SAGE Publications Inc.", issn = "0883-0738, 1708-8828", doi = "10.1177/08830738060210101401", abstract = "Acute necrotizing encephalopathy of childhood is a novel type of parainfectious encephalopathy with a racial and geographic predilection, rarely reported from other than East Asian areas. The objective was to describe the clinical, imaging, and other laboratory findings of non-Asian patients with acute necrotizing encephalopathy. Data were collected from three patients diagnosed in Athens over a 4-year period plus 16 cases reported from other European and North American countries. One of the Greek children died, and the other two had a normal outcome. A neuropathologic examination in the fatal case showed edematous necrosis without inflammatory, reactive, or proliferative changes. Data from Greek and other non-Asian patients support the homogeneity of the disease worldwide." }