@article{3117217, title = "Ovarian endometriosis associated with ovarian cancer and endometrial-endocervical polyps", author = "Kontoravdis, Antonios and Augoulea, Areti and Lambrinoudaki, Irene and and Christodoulakos, George and Tzortziotis, Dimitrios and Grammatikakis, and Ioannis and Kontoravdis, Nikolaos and Creatsas, George", journal = "Journal of Obstetrics and Gynaecology Research", year = "2007", volume = "33", number = "3", pages = "294-298", publisher = "Wiley", issn = "1341-8076, 1447-0756", doi = "10.1111/j.1447-0756.2007.00527.x", keywords = "endocervical polyp; endometrial polyp; endometriosis; ovarian cancer", abstract = "Aim: To determine the prevalence of ovarian cancer and endometrial polyps in women with moderate and severe ovarian endometriosis. Methods: A retrospective analysis of 667 cases of moderate and severe endometriosis laparoscopically and histologically confirmed during the period 1997-2004. Results: One hundred and ninety-three (29%) of cases were American Fertility Society (AFS) stage III (moderate endometriosis) and 473 (71%) were AFS stage IV (severe endometriosis). Ovarian cancer was diagnosed in 13 cases (2.0%), while an endometrial or endocervical polyp was identified in 35 cases (5.3%). The incidence of endometrial polyps in the group with moderate endometriosis tended to be higher (15/193, 7.8%) than in the group with severe endometriosis (20/473, 4.2%), and the same results were obtained in the ovarian cancer group (moderate: 6/193, 3.1%; severe: 7/473, 1.5%). However, neither of the two differences was statistically significant. Conclusions: Ovarian endometriosis may be associated with an increased incidence of both ovarian cancer and endometrial polyps. Careful evaluation for coexistent pathology should be undertaken in women with symptomatic endometriosis." }