@article{3119124,
    title = "Beta Blockers and Chronic Obstructive Pulmonary Disease (COPD): Sum of Evidence",
    author = "Baou, K. and Katsi, V. and Makris, T. and Tousoulis, D.",
    journal = "Current Hypertension Reviews",
    year = "2021",
    volume = "17",
    number = "3",
    pages = "196-206",
    publisher = "Bentham Science Publishers",
    issn = "1573-4021",
    doi = "10.2174/1573402116999201209203250",
    keywords = "acebutolol;  atenolol;  beta adrenergic receptor blocking agent;  betaxolol;  bisoprolol fumarate;  carvedilol;  esmolol;  labetalol;  metoprolol;  nadolol;  nebivolol;  penbutolol;  pindolol;  propranolol;  sotalol;  timolol;  beta adrenergic receptor blocking agent, all cause mortality;  angina pectoris;  atrial fibrillation;  cardiovascular disease;  cardiovascular mortality;  chronic obstructive lung disease;  coronary artery bypass graft;  forced expiratory volume;  heart failure;  heart infarction;  heart ventricle arrhythmia;  hypertension;  lung disease;  lung function;  migraine;  respiratory tract disease;  Review;  cardiovascular disease;  chronic obstructive lung disease;  heart arrhythmia;  heart failure;  human, Adrenergic beta-Antagonists;  Arrhythmias, Cardiac;  Cardiovascular Diseases;  Heart Failure;  Humans;  Pulmonary Disease, Chronic Obstructive",
    abstract = "Approximately half a century has passed since the discovery of beta-blockers. Then, their prime therapeutic purpose was to treat angina and cardiac arrhythmias; nowadays, beta-blockers’ usage and effectiveness are extended to treat other cardiovascular diseases, such as hypertension, congestive heart failure, and coronary artery disease. Safety concerns were raised about beta-blockers and their use for chronic obstructive pulmonary disease (COPD) patients with concurrent cardiovascular disease. After thorough research of the literature, this review summarizes the evidence proving that beta-blockers not only might be well tolerated in COPD patients, but they might also have a beneficial effect in this group of patients. © 2021 Bentham Science Publishers."
}