@article{3119723,
    title = "Unfractionated heparin reduces hepcidin levels in critically ill patients",
    author = "Vagionas, D. and Politou, M. and Kompoti, M. and Papadakis, D.-D. and Kostakou, E. and Theodoulou, D. and Kaniaris, E. and Rovina, N. and Koutsoukou, A. and Vasileiadis, I.",
    journal = "Internal Medicine Journal",
    year = "2021",
    volume = "51",
    number = "5",
    pages = "797-801",
    publisher = "John Wiley and Sons Inc",
    issn = "1444-0903, 1445-5994",
    doi = "10.1111/imj.15317",
    keywords = "C reactive protein;  creatinine;  heparin;  hepcidin;  heparin;  hepcidin, aged;  APACHE;  Article;  biochemistry;  blood sampling;  chemiluminescence immunoassay;  chemiluminescent microparticle immunoassay;  chronic obstructive lung disease;  clinical article;  critically ill patient;  disease exacerbation;  dose response;  drug dose increase;  enzyme linked immunosorbent assay;  female;  heart failure;  heart infarction;  hospital admission;  hospitalization;  human;  intensive care unit;  limb ischemia;  male;  mortality;  non invasive procedure;  observational study;  polyserositis;  prospective study;  renal replacement therapy;  septic shock;  treatment duration;  anemia;  critical illness, Anemia;  Critical Illness;  Heparin;  Hepcidins;  Humans",
    abstract = "A strong anti-hepcidin activity has been observed in heparins. Mean hepcidin levels were significantly reduced compared to baseline, following the first day of unfractionated heparin administration in critically patients. Heparin displayed a strong independent negative association with hepcidin. These results may lead to future treatment methods of forms of anaemia characterised by hepcidin excess, common among the critically ill. © 2021 Royal Australasian College of Physicians"
}