@article{3120231,
    title = "Assessment of Anatomical and Functional Macular Changes with Optical Coherence Tomography Angiography After Macula-Off Rhegmatogenous Retinal Detachment Repair.",
    author = "Christou, E.E. and Kalogeropoulos, C. and Georgalas, I. and Stavrakas, P. and Christodoulou, E. and Batsos, G. and Stefaniotou, M.",
    journal = "Seminars in Ophthalmology",
    year = "2021",
    volume = "36",
    number = "3",
    pages = "119-127",
    publisher = "Taylor and Francis Ltd.",
    issn = "0882-0538, 1744-5205",
    doi = "10.1080/08820538.2021.1889618",
    keywords = "adult;  article;  blood vessel density;  capillary;  case control study;  clinical article;  controlled study;  female;  human;  male;  optical coherence tomography angiography;  pars plana vitrectomy;  retina detachment surgery;  retina macula lutea;  retrospective study;  diagnostic imaging;  fluorescence angiography;  optical coherence tomography;  retina blood vessel;  retina detachment;  visual acuity;  vitrectomy, Case-Control Studies;  Fluorescein Angiography;  Humans;  Macula Lutea;  Retinal Detachment;  Retinal Vessels;  Retrospective Studies;  Tomography, Optical Coherence;  Visual Acuity;  Vitrectomy",
    abstract = "Purpose: To evaluate macular capillary plexus changes with OCT-angiography with regard to macular detachment duration in macula-off rhegmatogenous retinal detachment (RRD). Methods: 23 eyes of 23 patients were included in this retrospective case–control study and were divided into 2 groups. Group-A had a macular detachment duration of 0 to 10 days and group-B of 11 to 30 days. All eyes underwent a single successful pars plana vitrectomy (PPV) and gas tamponade. We analysed the OCT-A characteristics and visual outcomes at 12 weeks postoperatively in the 2 groups. The fellow eye was used as control. Results: Vessel density (VD) and flow density (FD) in the superficial capillary plexus (SCP) were significantly lower in group-B (p < .01) than in group-A and control. FAZ SCP in both groups was significantly larger than the control (p < .01), although it did not differ significantly between the two groups (p = 1.000). BCVA was significantly lower in group-B compared to group-A (p < .01). BCVA was positively correlated with VD SCP in group B (p = .015), but not in group-A. Postoperative BCVA had no correlation with FAZ SCP in both groups. Conclusions: The macular detachment duration could be a predicting factor of flow density in macular capillary plexus which in turn might be an indicator of visual outcomes in chronic cases. © 2021 Taylor & Francis."
}