@article{3121082,
    title = "Relaxation training significantly reduced blood glucose levels in patients with type 1 diabetes mellitus",
    author = "Paschali, A.A. and Peppou, L.Ε. and Benroubi, M.",
    journal = "Vitamins and Hormones",
    year = "2020",
    volume = "19",
    number = "2",
    pages = "215-222",
    publisher = "Springer-Verlag",
    doi = "10.1007/s42000-020-00187-w",
    keywords = "hemoglobin A1c;  placebo;  glycosylated hemoglobin;  hemoglobin A1c protein, human, adult;  age distribution;  Article;  body weight;  checklist;  cholesterol blood level;  circulation time;  clinical article;  clinical practice;  controlled study;  female;  glucose blood level;  glucose urine level;  hemoglobin blood level;  human;  insulin dependent diabetes mellitus;  Likert scale;  male;  Mood Adjective Checklist;  quality of life;  randomized controlled trial;  relaxation training;  State Trait Anxiety Inventory;  anxiety;  blood;  glucose blood level;  insulin dependent diabetes mellitus;  kinesiotherapy;  metabolism;  multimodality cancer therapy;  therapy;  treatment outcome, Adult;  Anxiety;  Blood Glucose;  Combined Modality Therapy;  Diabetes Mellitus, Type 1;  Exercise Therapy;  Female;  Glycated Hemoglobin A;  Humans;  Male;  Relaxation Therapy;  Treatment Outcome",
    abstract = "Purpose/Objective: The present study was designed to test whether adding a relaxation training technique to the medical treatment of patients with type 1 diabetes mellitus could, adjusting for the non-specific factors of therapy, lead to an improvement in the patients’ condition. Method: Forty-six participants were randomly allocated either to an experimental (intervention) group, receiving weekly sessions of relaxation training, or to a control group (placebo) receiving weekly blood circulation training exercises. Measures included the State and Trait Anxiety Inventory, blood glucose levels, high-density lipoprotein levels, cholesterol levels, body weight, HbA1c levels, the Mood Adjective Checklist (MACL), a diary checklist, and urine glucose levels. Assessment of psychological and physiological parameters was conducted before and upon completion of the intervention (8 weeks). Results: Trait anxiety and the main metabolic measurement of blood glucose levels and HbA1C revealed significant differences over time, predominantly among patients in the intervention group. Conclusions: Relaxation techniques as an adjunct to medical treatment are a useful tool for patients with type 1 diabetes mellitus. © 2020, Hellenic Endocrine Society."
}