@article{3121138,
    title = "Is Single-Incision Laparoscopic Liver Surgery Safe and Efficient for the Treatment of Malignant Hepatic Tumors? A Systematic Review",
    author = "Machairas, N. and Papaconstantinou, D. and Gaitanidis, A. and Hasemaki, N. and Paspala, A. and Stamopoulos, P. and Kykalos, S. and Sotiropoulos, G.C.",
    journal = "Journal of Gastrointestinal Cancer",
    year = "2020",
    volume = "51",
    number = "2",
    pages = "425-432",
    publisher = "Springer-Verlag",
    issn = "1941-6628, 1941-6636",
    doi = "10.1007/s12029-019-00285-y",
    keywords = "cancer surgery;  clinical effectiveness;  human;  incision;  laparoscopic surgery;  laparoscopy;  length of stay;  liver cell carcinoma;  liver metastasis;  liver resection;  liver surgery;  liver tumor;  morbidity;  multiport incision laparoscopic liver surgery;  open surgery;  operation duration;  operative blood loss;  postoperative complication;  priority journal;  Review;  safety procedure;  single incision laparoscopic liver surgery;  single port laparoscopic liver surgery;  surgical mortality;  systematic review;  adult;  aged;  female;  liver tumor;  male;  middle aged;  pathology;  procedures;  retrospective study;  very elderly, Adult;  Aged;  Aged, 80 and over;  Carcinoma, Hepatocellular;  Female;  Hepatectomy;  Humans;  Laparoscopy;  Liver Neoplasms;  Male;  Middle Aged;  Retrospective Studies",
    abstract = "Purpose: The objective of this review was to evaluate the safety and efficiency of single-incision laparoscopic liver surgery (SILLS) for malignant liver lesions. Methods: A retrospective review of the Medline database was performed, including studies published up to February 2019. Results: Overall, 69 patients (50 males) with a median age of 61 years (range, 31–90) from 16 studies underwent SILLS for malignant liver disease and were included in this review. The majority of patients underwent resection for hepatocellular carcinoma (n = 52, 75 %), followed by metastatic disease (n = 15, 22 %). The hepatic lesions were located in anterolateral liver segments in 62 patients (90 %) and in posterosuperior liver segments in 7 patients (10 %). Sixty-five patients (94 %) underwent minor liver resection. The median blood loss was 200 mL (range 0–2500), while 4 patients that underwent single-port resection were converted to either conventional laparoscopy or open resections. Two cases were reported to be associated with postoperative complications in the single-port group (1 [1.7 %] grade Dindo-Clavien I–II, 1 [1.7 %] grade Dindo-Clavien III–IV), while no complications were noted in the multiport group. All patients successfully underwent R0 resection. Conclusions: SILLS seems to be a safe and efficient treatment modality for malignant liver disease when performed by experienced surgeons in carefully selected patients. More studies are needed to better identify which patients may benefit from such an operative approach. © 2019, Springer Science+Business Media, LLC, part of Springer Nature."
}