@article{3122184, title = "Long-term Effects of Treatment for Chronic HBV Infection on Patient-Reported Outcomes", author = "Younossi, Z.M. and Stepanova, M. and Younossi, I. and Pan, C.Q. and Janssen, H.L.A. and Papatheodoridis, G. and Nader, F.", journal = "Clinical Gastroenterology and Hepatology", year = "2019", volume = "17", number = "8", pages = "1641-1642.e1", publisher = "W.B. Saunders", issn = "1542-3565, 1542-7714", doi = "10.1016/j.cgh.2018.09.041", keywords = "adefovir; entecavir; lamivudine; telbivudine; antivirus agent; virus DNA, adult; antiviral therapy; Asian; female; hepatitis B; human; major clinical study; male; mental health; patient-reported outcome; physical functioning score; population research; presenteeism; productivity; scoring system; Short Form 36; Short Survey; United States; viremia; chronic hepatitis B; follow up; genetics; Hepatitis B virus; middle aged; register; retrospective study; time factor; virology, Antiviral Agents; DNA, Viral; Female; Follow-Up Studies; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Middle Aged; Patient Reported Outcome Measures; Registries; Retrospective Studies; Time Factors", abstract = "Worldwide, viral hepatitis remains the most common cause of chronic liver disease.1 In this context, hepatitis B virus (HBV) infection and its complications are responsible for a tremendous clinical burden related to cirrhosis and hepatocellular carcinoma.1 In contrast, long-term HBV suppression can improve hepatic fibrosis and clinical outcomes.2 © 2019 AGA Institute" }