@article{3122210,
    title = "Open Repair of a Ruptured Abdominal Aortic Aneurysm on a Patient Under Rivaroxaban and Clopidogrel",
    author = "Poulou, A. and Alexiou, E. and Geroulakos, G. and Lazaris, A.M.",
    journal = "Annals of Vascular Surgery",
    year = "2019",
    volume = "58",
    pages = "379.e5-379.e8",
    publisher = "HANLEY & BELFUS-ELSEVIER INC",
    issn = "0890-5096",
    doi = "10.1016/j.avsg.2018.09.042",
    keywords = "clopidogrel;  creatinine;  D dimer;  fibrinogen;  fresh frozen plasma;  hemoglobin;  heparin;  low molecular weight heparin;  polyester;  protamine sulfate;  rivaroxaban;  antithrombocytic agent;  blood clotting factor 10a inhibitor;  clopidogrel;  rivaroxaban, abdominal aortic aneurysm;  abdominal pain;  adult;  anticoagulant therapy;  aortic rupture;  arterial pressure;  Article;  atrial fibrillation;  case report;  clinical article;  computer assisted tomography;  creatinine blood level;  creatinine clearance;  heart infarction;  hemoglobin blood level;  hernioplasty;  human;  hypertension;  inguinal hernia;  international normalized ratio;  intraoperative period;  laboratory test;  laparotomy;  leukocyte count;  lithotripsy;  low back pain;  male;  medical history;  middle aged;  multiple sclerosis;  nephrolithiasis;  platelet count;  priority journal;  prothrombin time;  pulse rate;  transluminal coronary angioplasty;  transurethral resection;  abdominal aortic aneurysm;  aortic rupture;  aortography;  blood vessel prosthesis;  blood vessel transplantation;  computed tomographic angiography;  devices;  diagnostic imaging;  drug administration;  emergency;  heart infarction;  percutaneous coronary intervention;  procedures;  treatment outcome, Aortic Aneurysm, Abdominal;  Aortic Rupture;  Aortography;  Blood Vessel Prosthesis;  Blood Vessel Prosthesis Implantation;  Clopidogrel;  Computed Tomography Angiography;  Drug Administration Schedule;  Emergencies;  Factor Xa Inhibitors;  Humans;  Male;  Middle Aged;  Myocardial Infarction;  Percutaneous Coronary Intervention;  Platelet Aggregation Inhibitors;  Rivaroxaban;  Treatment Outcome",
    abstract = "Background: Direct oral anticoagulants are commonly used instead of vitamin K antagonists in patients needing long-term anticoagulant treatment. As their use has become more popular, there is an increase possibility to perform a major surgery on an urgent or emergency basis on patients under nonvitamin–K antagonist oral anticoagulants. Case report: We report a case of a ruptured abdominal aortic aneurysm on a male patient under rivaroxaban and clopidogrel. Emergency open repair of the aneurysm was performed. No anti-Xa antidote was administered. The patient had an uneventful recovery. Conclusion: An open repair of a ruptured abdominal aortic aneurysm under rivaroxaban is feasible. However, an antidote should be available in cases of uncontrolled diffused bleeding. To the best of our knowledge, this is the first reported case of successful open repair of a ruptured abdominal aortic aneurysm on a patient under rivaroxaban and clopidogrel. © 2019"
}