@article{3123392,
    title = "Optical Biometry Derived Axial Length Measurements Following Intravitreal Anti-Vascular Endothelial Growth Factor Treatment for Macular Edema",
    author = "Kymionis, G.D. and Giarmoukakis, A. and Apostolidi, I.K. and Blazaki, S.V. and Tsoulnaras, K.I. and Moschandrea, J. and Panagopoulou, S. and Tsilimbaris, M.K.",
    journal = "Seminars in Ophthalmology",
    year = "2018",
    volume = "33",
    number = "4",
    pages = "488-491",
    publisher = "Taylor and Francis Ltd.",
    issn = "0882-0538, 1744-5205",
    doi = "10.1080/08820538.2017.1303520",
    keywords = "ranibizumab;  angiogenesis inhibitor;  ranibizumab;  vasculotropin A, aged;  Article;  biometry;  central retinal thickness;  clinical article;  comparative study;  controlled study;  eye axis length;  female;  follow up;  human;  macular edema;  male;  observational study;  priority journal;  prospective study;  spectral domain optical coherence tomography;  antagonists and inhibitors;  biometry;  diagnostic imaging;  eye axis length;  eye fundus;  fluorescence angiography;  intravitreal drug administration;  macular edema;  optical coherence tomography;  pathology;  pathophysiology;  procedures;  retina macula lutea;  visual acuity, Aged;  Angiogenesis Inhibitors;  Axial Length, Eye;  Biometry;  Female;  Fluorescein Angiography;  Fundus Oculi;  Humans;  Intravitreal Injections;  Macula Lutea;  Macular Edema;  Male;  Prospective Studies;  Ranibizumab;  Tomography, Optical Coherence;  Vascular Endothelial Growth Factor A;  Visual Acuity",
    abstract = "Purpose: To evaluate axial length (AL) alterations in patients with macular disease over the course of intravitreal anti-vascular endothelial growth factor (anti-VEGF) treatment. Methods: In this prospective, comparative study, 33 patients with macular edema underwent unilaterally intravitreal anti-VEGF therapy and were followed for two months; the contralateral eyes were considered as controls. Central retinal thickness (CRT) was measured with spectral-domain optical coherence tomography and AL with an IOL-Master optical biometer. Results: CRT of the treated eyes decreased by 35.33 ± 65.59 μm (range, –222.00–67 μm), while AL increased by 0.008 ± 0.062 mm (range, –0.11–0.18 mm). CRT of the control group decreased by 9.82 ± 65.40 μm (range, –203–182 μm), and AL increased by 0.011 ± 0.129 mm (range, –0.20–0.67 mm). No significant correlation was detected between CRT and AL parameters (rhos=0.026, P=0.882). Conclusions: Anti-VEGF administration has no significant impact on optical biometry-derived AL measurements. © Taylor & Francis."
}