@article{3123596,
    title = "Management, outcomes, and prognostic factors of ruptured hepatocellular carcinoma: A systematic review",
    author = "Moris, D. and Chakedis, J. and Sun, S.H. and Spolverato, G. and Tsilimigras, D.I. and Ntanasis-Stathopoulos, I. and Spartalis, E. and Pawlik, T.M.",
    journal = "International Journal of Surgical Oncology",
    year = "2018",
    volume = "117",
    number = "3",
    pages = "341-353",
    publisher = "John Wiley and Sons Inc",
    issn = "2090-1402, 2090-1410",
    doi = "10.1002/jso.24869",
    keywords = "bleeding;  cancer prognosis;  cancer survival;  cancer therapy;  clinical feature;  clinical outcome;  human;  liver cell carcinoma;  liver resection;  liver rupture;  priority journal;  Review;  systematic review;  ablation therapy;  chemoembolization;  female;  liver cell carcinoma;  liver tumor;  male;  middle aged;  pathology;  retrospective study;  rupture;  treatment outcome, Ablation Techniques;  Carcinoma, Hepatocellular;  Chemoembolization, Therapeutic;  Female;  Hepatectomy;  Humans;  Liver Neoplasms;  Male;  Middle Aged;  Retrospective Studies;  Rupture, Spontaneous;  Treatment Outcome",
    abstract = "Ruptured hepatocellular (rHCC) is a rare but life-threatening presentation that often requires acute intervention. In this systematic review we identified 67 eligible studies reporting on 4941 patients with rHCC. Here we present the treatment approaches for the management of rHCC both in the acute setting with regards to management of hemorrhage, as well long-term with regards to oncological treatment. © 2017 Wiley Periodicals, Inc."
}