@article{3125493,
    title = "An unusual case of acute kidney injury - idiopathic granulomatous tubulointerstitial nephritis",
    author = "Balafa, O. and Liapis, G. and Duni, A. and Xiromeriti, S. and Kalaitzidis, R. and Elisaf, M.",
    journal = "Clinical Nephrology",
    year = "2015",
    volume = "84",
    number = "4",
    pages = "247-250",
    publisher = "Dustri Verlag/Dr. Karl Feistle",
    issn = "0301-0430",
    doi = "10.5414/CN108543",
    keywords = "acetylsalicylic acid;  amiloride;  C reactive protein;  creatinine;  furosemide;  hemoglobin;  methylprednisolone;  omeprazole;  pravastatin;  propafenone;  urea, acute kidney failure;  aged;  Article;  blood examination;  case report;  colon tumor;  computer assisted tomography;  creatinine blood level;  erythrocyte sedimentation rate;  female;  heart arrhythmia;  hemoglobin blood level;  hospital admission;  human;  human tissue;  idiopathic disease;  idiopathic granulomatous tubulointerstitial nephritis;  incidental finding;  interstitial nephritis;  leukocyte count;  pacemaker implantation;  parathyroid adenomectomy;  patient history of surgery;  periodic medical examination;  protein blood level;  rare disease;  sigmoid polyp;  thorax radiography;  thyroid surgery;  tissue section;  urea blood level;  Acute Kidney Injury;  complication;  granuloma;  interstitial nephritis;  kidney;  pathology, Acute Kidney Injury;  Aged;  Female;  Granuloma;  Humans;  Kidney;  Nephritis, Interstitial",
    abstract = "We present a case which emphasizes the importance of performing a kidney biopsy in each case of acute kidney injury (AKI) of unknown etiology. The unexpected histological diagnosis of granulomatous interstitial nephritis (GIN) is a rare cause of AKI. The main causes of GIN include drugs (NSAIDs, antibiotics), sarcoidosis, and infections (mycobacterial and fungal). In our case, a 68-year-old woman was admitted with AKI, absence of symptoms and unremarkable history, apart from coronary heart disease. Renal biopsy was performed, since history as well as clinical and laboratory data could not define a cause of AKI. A more meticulous clinical and laboratory investigation followed the histological diagnosis in order to rule out sarcoidosis, vasculitis or any other known causes of GIN. Finally the diagnosis was characterized as AKI due to idiopathic GIN. The patient responded well to corticosteroids. © 2015 Dustri-Verlag Dr. K. Feistle."
}