@article{3126129, title = "Challenging differential diagnosis of an extra-adrenal paraganglioma; the role of fine needle aspiration cytology", author = "Ntanasis-Stathopoulos, I. and Tsilimigras, D.I. and Klapsinou, E. and Daskalopoulou, D. and Vaida, S. and Arnogiannaki, N. and Salla, C.", journal = "Diagnostic Cytopathology", year = "2017", volume = "45", number = "6", pages = "565-568", publisher = "John Wiley and Sons Inc", issn = "8755-1039, 1097-0339", doi = "10.1002/dc.23696", keywords = "antineoplastic agent; CD56 antigen; chromogranin; cisplatin; neuron specific enolase; protein S 100; synaptophysin; transcription factor GATA 3; unclassified drug; vepecial; vimentin, adult; Article; cancer radiotherapy; case report; cervical spine radiography; chromatin; clinical feature; diagnostic error; differential diagnosis; female; fine needle aspiration biopsy; human; human cell; human tissue; immunocytochemistry; lung metastasis; medical history; neck; neck pain; neck paraganglioma; nuclear magnetic resonance imaging; paraganglioma; patient referral; priority journal; retroperitoneal tumor; thorax radiography; tuberculosis; chemodectoma; differential diagnosis; fine needle aspiration biopsy; head and neck tumor; lung tumor; metastasis; pathology, Adult; Biopsy, Fine-Needle; Diagnosis, Differential; Female; Head and Neck Neoplasms; Humans; Lung Neoplasms; Neoplasm Metastasis; Paraganglioma, Extra-Adrenal", abstract = "Paragangliomas are rare neoplasms that arise from neural crest cells of the autonomous system. Herein, we present a case of a 37-year-old patient with a history of retroperitoneal paraganglioma and tuberculous infection presenting with a paraganglioma of the neck that was initially misdiagnosed as metastatic tumor originating from the lungs. Cytological features from fine needle aspiration and immunocytochemistry pointed to the right diagnosis. However, distinguishing between primary and metastatic site of a paraganglioma can be very challenging due to the overlapping features of these entities. Furthermore, this case underlines the value of a detailed medical history in the era of modern diagnostic modalities. Diagn. Cytopathol. 2017;45:565–568. © 2017 Wiley Periodicals, Inc. © 2017 Wiley Periodicals, Inc." }