@article{3126275, title = "Dark Adaptation in Patients with Primary Open-Angle Glaucoma, Pseudoexfoliation Glaucoma and Childhood Glaucoma", author = "Panos, G.D. and Moschos, M.M. and Kozeis, N. and Deshmukh, R.R. and Mansouri, K. and Shaarawy, T. and Gatzioufas, Z.", journal = "Klinische Monatsblätter für Augenheilkunde", year = "2017", volume = "234", number = "4", pages = "464-467", publisher = "Georg Thieme Verlag", doi = "10.1055/s-0042-119562", keywords = "adult; analysis of variance; Article; child; childhood glaucoma; dark adaptation; flow measurement; glaucoma; human; major clinical study; middle aged; open angle glaucoma; perfusion; pseudoexfoliation glaucoma; retina cone; retina rod; retinal tomography; scanning laser retinal flowmetry; school child; tomography; complication; female; male; open angle glaucoma; pathophysiology; perimetry; pseudoexfoliation; visual acuity; visual disorder; visual field, Dark Adaptation; Exfoliation Syndrome; Female; Glaucoma, Open-Angle; Humans; Male; Middle Aged; Vision Disorders; Visual Acuity; Visual Field Tests; Visual Fields", abstract = "Purpose To investigate the state of dark adaptation and macular blood flow in different forms of glaucoma. Methods Eighteen eyes of 18 patients with primary open-angle glaucoma, 14 eyes of 14 patients with pseudoexfoliation glaucoma, and 10 eyes of 10 patients with childhood glaucoma (CG) were examined by means of dark adaptometry, scanning-laser retinal flowmetry, and retinal tomography. Results All glaucomatous eyes had comparable optic disc excavation (one-way ANOVA, p = 0.138). Eyes with CG had significantly lower best-corrected visual acuity than the other groups (Tukey, all p <0.0001). Macular perfusion was comparable in all three groups (one – way ANOVA, p = 0.08). The delay in rod-cone break time in the CG group was significantly higher than in the other groups (Tukey, all p <0.0001). The scotopic sensitivity threshold in the CG group was significantly greater than in the other groups (Tukey, all p <0.01). Conclusion This underlying dysfunction of dark adaptation may contribute, at least to some extent, to the decreased visual perception observed in patients with CG. © Georg Thieme Verlag KG Stuttgart · New York." }