@article{3130078,
    title = "Whole blood interferon-γ release assay is a useful tool for the diagnosis of tuberculosis infection particularly among bacille calmette guèrin-vaccinated children",
    author = "Tsolia, M.N. and Mavrikou, M. and Critselis, E. and Papadopoulos, N.G. and Makrinioti, H. and Spyridis, N.P. and Metsou, F. and Tsagaraki, M. and Koulouri, M. and Kafetzis, D.A.",
    journal = "The Pediatric Infectious Disease Journal",
    year = "2010",
    volume = "29",
    number = "12",
    pages = "1137-1140",
    issn = "0891-3668, 1532-0987",
    doi = "10.1097/INF.0b013e3181ebfe8a",
    keywords = "BCG vaccine;  gamma interferon, article;  BCG vaccination;  child;  controlled study;  cytokine release;  diagnostic test accuracy study;  human;  intermethod comparison;  latent tuberculosis;  major clinical study;  pediatrics;  priority journal;  protein determination;  sensitivity and specificity;  skin test;  tuberculin test;  tuberculosis, Adolescent;  BCG Vaccine;  Blood;  Cells, Cultured;  Child;  Child, Preschool;  Diagnosis, Differential;  Humans;  Infant;  Infant, Newborn;  Interferon-gamma;  Sensitivity and Specificity;  Tuberculin Test;  Tuberculosis",
    abstract = "The performance of QuantiFERON-tuberculosis (TB) Gold-In-Tube assay was compared with the tuberculin skin test for the diagnosis of TB among children. It was shown that among non-Bacille Calmette Guèrin immunized children, agreement between tests was excellent both in those with TB disease and in TB contacts. Among Bacille Calmette Guèrin-immunized children, agreement was fair in those with active disease and poor among TB contacts. It is concluded that QuantiFERON-TB Gold-In-Tube compares with the tuberculin skin test in the diagnosis of TB disease and latent tuberculosis infection in TB contacts among children and has enhanced specificity. © 2010 Lippincott Williams & Wilkins."
}