@article{3134509, title = "Subtle infective endocarditis and congenital cardiac disease", author = "Chatzis, A.C. and Saroglou, G. and Giannopoulos, N.M. and Sarris, G.E.", journal = "Cardiology in the Young", year = "2005", volume = "15", number = "6", pages = "617-620", issn = "1047-9511, 1467-1107", doi = "10.1017/S1047951105001794", keywords = "ceftriaxone; dicloxacillin; gentamicin; penicillin G; rifampicin; vancomycin, adult; aneurysm rupture; aorta sinus aneurysm; aorta valve regurgitation; bacterial endocarditis; case report; clinical feature; congenital heart disease; echocardiography; Fallot tetralogy; female; heart catheterization; heart ventricle septum defect; human; intraoperative period; laboratory test; male; medical literature; nonhuman; preoperative evaluation; preschool child; review; surgical technique; treatment outcome, Adult; Anti-Infective Agents; Child, Preschool; Drug Therapy, Combination; Endocarditis, Subacute Bacterial; Female; Heart Aneurysm; Heart Septal Defects, Ventricular; Humans; Male; Tetralogy of Fallot", abstract = "Congenital cardiac disease is recognized as a major predisposing substrate for infective endocarditis. We present three cases of unanticipated intraoperative discovery of vegetations in patients with congenital cardiac malformations without preoperative clinical, laboratory or echocardiographic evidence of infective endocarditis, and their successful treatment. The relevant literature is reviewed, with emphasis of the need to maintain a high index of suspicion for the presence of endocarditis during repair of congenital cardiac lesions. © Cambridge University Press." }