@article{3149762,
    title = "RANIBIZUMAB FOR THE TREATMENT OF EXUDATIVE AGE-RELATED MACULAR
DEGENERATION ASSOCIATED WITH RETINAL PIGMENT EPITHELIAL TEAR",
    author = "Rouvas, Alexandros A. and Ladas, Ioannis D. and Georgalas, Ilias and and Vergados, Ioannis and Papakonstantinou, Dimitrios and Kotsolis, and Athanasios I.",
    journal = "RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES",
    year = "2011",
    volume = "31",
    number = "6",
    pages = "1083-1088",
    publisher = "Lippincott, Williams & Wilkins",
    doi = "10.1097/IAE.0b013e318207d1a3",
    keywords = "exudative age-related macular degeneration; ranibizumab; retinal pigment
epithelial tear",
    abstract = "Purpose: To evaluate the efficacy of intravitreal ranibizumab in eyes
with exudative age-related macular degeneration associated with retinal
pigment epithelial tear.
Methods: In this retrospective case series, patients with active
exudative age-related macular degeneration associated with retinal
pigment epithelial tear were treated by repeated injections of
intravitreal ranibizumab. The outcome measures were best-corrected
visual acuity and the signs of lesion activity, as evaluated by optical
coherence tomography, fluorescein angiography, and indocyanine green
angiography.
Results: Twenty-one eyes of 20 patients were followed-up for a median of
12 months (range, 6-28 months). The median number of injections was 7
(range, 3-15). The best-corrected visual acuity improved in 6 eyes
(28.57%), remained stable in 12 (57.14%), and decreased in 3
(14.28%). At the end of the follow-up time, 19 eyes (90.47%) had an
inactive neovascular lesion in angiography, while 18 eyes (85.71%) had
no signs of intraretinal or subretinal fluid.
Conclusion: Intravitreal ranibizumab was effective in improving or
stabilizing vision and resulting in a quiescent lesion in the majority
of patients with exudative age-related macular degeneration associated
with retinal pigment epithelial tear. The functional results were
apparently better in eyes without foveal involvement by the retinal
pigment epithelial tear. RETINA 31:1083-1088, 2011"
}