@article{3154577,
    title = "Glaucoma risk assessment using a non-linear multivariable regression
method",
    author = "Kourkoutas, D. and Karanasiou, I. S. and Tsekouras, G. J. and Moshos, M. and and Iliakis, E. and Georgopoulos, G.",
    journal = "Computer Methods and Programs in Biomedicine",
    year = "2012",
    volume = "108",
    number = "3",
    pages = "1149-1159",
    publisher = "Elsevier Ireland Ltd",
    doi = "10.1016/j.cmpb.2012.08.004",
    keywords = "Central corneal thickness; Glaucoma; Non-linear multivariable regression
model; Heidelberg Retina Tomograph II",
    abstract = "The present research investigates the relationship between the central
corneal thickness (CCT), Heidelberg Retina Tomograph II (HRTII)
structural measurements and intraocular pressure (IOP) using an
innovative non-linear multivariable regression method in order to define
the risk factors in future glaucoma development and patient management.
The method is implemented to data from ninety-three open angle glaucoma
eyes. The results show that in established glaucoma, CCT is
significantly associated with HRTII structural measurements (maximum
contour depression, cup volume inferotemporally) and IOP. They are also
compared to those obtained from the application of standard linear
regression methods, improving the coefficient determination R-2 by 35%,
exhibiting thus the performance of the proposed methodology. (C) 2012
Elsevier Ireland Ltd. All rights reserved."
}