@article{3159989, title = "MICROBIOLOGY OF ACUTE MASTOIDITIS AND COMPLICATED OR REFRACTORY ACUTE OTITIS MEDIA AMONG HOSPITALIZED CHILDREN IN THE POSTVACCINATION ERA", author = "Giannakopoulos, Polyvios and Chrysovergis, Aristeidis and Xirogianni, and Athanasia and Nikolopoulos, Thomas P. and Radiotis, Alexandros and and Lebessi, Evangelia and Tsakanikos, Michail and Tzanakaki, Georgina and and Tsolia, Maria N.", journal = "The Pediatric Infectious Disease Journal", year = "2014", volume = "33", number = "1", pages = "111-113", publisher = "Lippincott, Williams & Wilkins", issn = "0891-3668, 1532-0987", doi = "10.1097/INF.0b013e3182a6adb7", keywords = "acute mastoiditis; refractory acute otitis media; complicated acute otitis media; Streptococcus pneumoniae serotype 19A; conjugate pneumococcal vaccine-heptavalent pneumococcal conjugate vaccine", abstract = "In the post-heptavalent pneumococcal conjugate vaccine era, Streptococcus pneumoniae remains the leading cause of acute mastoiditis and other complicated or refractory acute otitis media among hospitalized children in our settings. Serotype 19A is predominant, invasive and multidrug resistant causing more than half of all mastoiditis cases, two-thirds of cases with subperiosteal abscess and all those requiring mastoidectomy. Continuous surveillance is required." }