@article{3161750,
    title = "Dietary Fat Intake and Development of Specific Breast Cancer Subtypes",
    author = "Sieri, Sabina and Chiodini, Paolo and Agnoli, Claudia and Pala, Valeria and and Berrino, Franco and Trichopoulou, Antonia and Benetou, Vassiliki and and Vasilopoulou, Effie and Sanchez, Maria-Jose and Chirlaque, Maria-Dolores and and Amiano, Pilar and Ramon Quiros, J. and Ardanaz, Eva and Buckland, and Genevieve and Masala, Giovanna and Panico, Salvatore and Grioni, Sara and and Sacerdote, Carlotta and Tumino, Rosario and Boutron-Ruault, and Marie-Christine and Clavel-Chapelon, Francoise and Fagherazzi, Guy and and Peeters, Petra H. M. and van Gils, Carla H. and Bueno-de-Mesquita, H. and Bas and van Kranen, Henk J. and Key, Timothy J. and Travis, Ruth C. and and Khaw, Kay Tee and Wareham, Nicholas J. and Kaaks, Rudolf and Lukanova, and Annekatrin and Boeing, Heiner and Schuetze, Madlen and Sonestedt, Emily and and Wirfaelt, Elisabeth and Sund, Malin and Andersson, Anne and Chajes, and Veronique and Rinaldi, Sabina and Romieu, Isabelle and Weiderpass, and Elisabete and Skeie, Guri and Dagrun, Engeset and Tjonneland, Anne and and Halkjaer, Jytte and Overvard, Kim and Merritt, Melissa A. and Cox, David and and Riboli, Elio and Krogh, Vittorio",
    journal = "JNCI Journal of the National Cancer Institute",
    year = "2014",
    volume = "106",
    number = "5",
    publisher = "OXFORD UNIV PRESS INC",
    issn = "0027-8874, 1460-2105",
    doi = "10.1093/jnci/dju068",
    abstract = "We prospectively evaluated fat intake as predictor of developing breast
cancer (BC) subtypes defined by estrogen receptor (ER), progesterone
receptor (PR), and human epidermal growth factor 2 receptor (HER2), in a
large (n = 337 327) heterogeneous cohort of women, with 10 062 BC case
patients after 11.5 years, estimating BC hazard ratios (HRs) by Cox
proportional hazard modeling. High total and saturated fat were
associated with greater risk of ER+PR+ disease (HR = 1.20, 95%
confidence interval [CI] = 1.00 to 1.45; HR = 1.28, 95% CI = 1.09 to
1.52; highest vs lowest quintiles) but not ER-PR- disease. High
saturated fat was statistically significantly associated with greater
risk of HER2(-) disease. High saturated fat intake particularly
increases risk of receptor-positive disease, suggesting saturated fat
involvement in the etiology of this BC subtype."
}