@article{3165135,
    title = "Chronic severe constipation: current pathophysiological aspects, new
diagnostic approaches, and therapeutic options",
    author = "Andromanakos, Nikolaos P. and Pinis, Stamatis I. and Kostakis, and Alkiviadis I.",
    journal = "European Journal of Gastroenterology and Hepatology",
    year = "2015",
    volume = "27",
    number = "3",
    pages = "204-214",
    publisher = "Lippincott, Williams & Wilkins",
    issn = "0954-691X, 1473-5687",
    doi = "10.1097/MEG.0000000000000288",
    keywords = "colonic inertia; colonic slow transit; constipation; defecatory
disorders; dyssynergic pelvic floor; pelvic outlet obstruction",
    abstract = "Chronic constipation is a considerable problem because it significantly
affects the quality of a patient’s life. Constipation can be diagnosed
at every age and is more frequent in women and among the elderly. In
epidemiological studies, its incidence is estimated at 2-27% in the
general population. Chronic constipation may be primary or secondary.
However, primary constipation (functional or idiopathic) can be
classified into normal transit constipation, slow transit constipation,
and pelvic outlet obstruction. In this review we make an attempt to
present the current pathophysiological aspects and new therapeutic
options for chronic idiopathic constipation, particularly highlighting
the value of patient assessment for accurate diagnosis of the cause of
the problem, thus helping in the choice of appropriate treatment.
Copyright (C) 2015 Wolters Kluwer Health, Inc. All rights reserved."
}