@article{3167570,
    title = "Genome-Wide Association Study of Prostate Cancer-Specific Survival",
    author = "Szulkin, Robert and Karlsson, Robert and Whitington, Thomas and Aly, and Markus and Gronberg, Henrik and Eeles, Rosalind A. and Easton, Douglas and F. and Kote-Jarai, Zsofia and Al Olama, Ali Amin and Benlloch, Sara and and Muir, Kenneth and Giles, Graham G. and Southey, Melissa C. and and FitzGerald, Liesel M. and Henderson, Brian E. and Schumacher, Fredrick and R. and Haiman, Christopher A. and Sipeky, Csilla and Tammela, Teuvo L. and J. and Nordestgaard, Borge G. and Key, Timothy J. and Travis, Ruth C. and and Neal, David E. and Donovan, Jenny L. and Hamdy, Freddie C. and and Pharoah, Paul D. P. and Pashayan, Nora and Khaw, Kay-Tee and Stanford, and Janet L. and Thibodeau, Stephen N. and McDonnell, Shannon K. and Schaid, and Daniel J. and Maier, Christiane and Vogel, Walther and Luedeke, Manuel and and Herkommer, Kathleen and Kibel, Adam S. and Cybulski, Cezary and and Lubinski, Jan and Kluzniak, Wojciech and Cannon-Albright, Lisa and and Brenner, Hermann and Herrmann, Volker and Holleczek, Bernd and Park, and Jong Y. and Sellers, Thomas A. and Lim, Hui-Yi and Slavov, Chavdar and and Kaneva, Radka P. and Mitev, Vanio I. and Spurdle, Amanda and Teixeira, and Manuel R. and Paulo, Paula and Maia, Sofia and Pandha, Hardev and and Michael, Agnieszka and Kierzek, Andrzej and Batra, Jyotsna and Clements, and Judith A. and Albanes, Demetrius and Andriole, Gerald L. and Berndt, and Sonja I. and Chanock, Stephen and Gapstur, Susan M. and Giovannucci, and Edward L. and Hunter, David J. and Kraft, Peter and Le Marchand, Loic and and Ma, Jing and Mondul, Alison M. and Penney, Kathryn L. and Stampfer, and Meir J. and Stevens, Victoria L. and Weinstein, Stephanie J. and and Trichopoulou, Antonia and Bueno-de-Mesquita, Bas H. and Tjonneland, Anne and and Cox, David G. and Maehle, Lovise and Schleutker, Johanna and and Lindstroem, Sara and Wiklund, Fredrik and PRACTICAL Consortium and and Australian Prostate Canc BioResour and BPC3 Consortium",
    journal = "Cancer Epidemiology, Biomarkers & Prevention",
    year = "2015",
    volume = "24",
    number = "11",
    pages = "1796-1800",
    publisher = "AMER ASSOC CANCER RESEARCH",
    issn = "1055-9965, 1538-7755",
    doi = "10.1158/1055-9965.EPI-15-0543",
    abstract = "Background: Unnecessary intervention and overtreatment of indolent
disease are common challenges in clinical management of prostate cancer.
Improved tools to distinguish lethal from indolent disease are critical.
Methods: We performed a genome-wide survival analysis of cause-specific
death in 24,023 prostate cancer patients (3,513 disease-specific deaths)
from the PRACTICAL and BPC3 consortia. Top findings were assessed for
replication in a Norwegian cohort (CONOR).
Results: We observed no significant association between genetic variants
and prostate cancer survival.
Conclusions: Common genetic variants with large impact on prostate
cancer survival were not observed in this study.
Impact: Future studies should be designed for identification of rare
variants with large effect sizes or common variants with small effect
sizes. (C) 2015 AACR."
}