@article{3179625,
    title = "The effect of static compression on the progression of bone healing. An
experimental study on rabbits",
    author = "Kateros, Konstantinos and Galanakos, Spyridon P. and Sakellariou, and Vasileios I. and Khaldi, Lubna and Karachalios, Theophilos",
    journal = "Clinical Cases in Mineral and Bone Metabolism",
    year = "2018",
    volume = "15",
    number = "2",
    pages = "196-200",
    publisher = "CIC EDIZIONI INT",
    doi = "10.11138/ccmbm/2018.15.2.196",
    keywords = "static compression; fracture; healing; histomorphology; long bone",
    abstract = "We aimed to evaluate the effect of static compression on the progression
of mid-diaphyseal bone healing. For this purpose, we used thirty-six New
Zealand rabbits that were submitted to iatrogenic fracture of the tibial
diaphysis that was reduced and stabilized using external fixation, with
and without the application of static compression. Three-point bending
was applied in order to assess the mechanical strains of the tibial bone
healing. Samples from the callus were obtained in order to examine
histomorphologically the biomechanical effect of repeated compression at
the fracture site and to evaluate the progression of bone healing at
different time intervals. Statistically significant differences were
found between the three and six weeks concerning the parameters of
fracture load, stiffness and toughness in favor of the group submitted
to compression. Histomorphological evaluation confirmed that progression
of fracture healing was more rapid under compression loading. We
concluded that compression applied on the fracture edges enhances bone
healing."
}