@article{3179647,
    title = "European evidence-based guidelines on pancreatic cystic neoplasms",
    author = "Del Chiaro, Marco and Besselink, Marc G. and Scholten, Lianne and Bruno, and Marco J. and Cahen, Djuna L. and Gress, Thomas M. and van Hooft, Jeanin and E. and Lerch, Markus M. and Mayerle, Julia and Hackert, Thilo and Satoi, and Sohei and Zerbi, Alessandro and Cunningham, David and De Angelis, and Claudio and Giovanni, Marc and de-Madaria, Enrique and Hegyi, Peter and and Rosendahl, Jonas and Friess, Helmut and Manfredi, Riccardo and Levy, and Philippe and Real, Francisco X. and Sauvanet, Alain and Abu Hilal, and Mohammed and Marchegiani, Giovanni and Esposito, Irene and Ghaneh, Paula and and Engelbrecht, Marc R. W. and Fockens, Paul and van Huijgevoort, and Nadine C. M. and Wolfgang, Christopher and Bassi, Claudio and and Gubergrits, Natalya B. and Verbeke, Caroline and Kloppel, Gunter and and Scarpa, Aldo and Zamboni, Giuseppe and Lennon, Anne Marie and Sund, and Malin and Kartalis, Nikolaos and Grenacher, Lars and Falconi, Massimo and and Arnelo, Urban and Kopchak, Kostantin V. and Oppong, Kofi and McKay, and Colin and Hauge, Truls and Conlon, Kevin and Adham, Mustapha and Ceyhan, and Guralp O. and Salvia, Roberto and Dervenis, Christos and Allen, Peter and and Paye, Francois and Bartsch, Detlef K. and Lohr, Matthias and and Mutignani, Massimiliano and Laukkarinen, Johanna and Schulick, Richard and and Valente, Roberto and Seufferlein, Thomas and Capurso, Gabriele and and Siriwardena, Ajith and Neoptolemos, John P. and Pukitis, Aldis and and Segersvard, Ralf and Aghdassi, A. and Andrianello, S. and Bossuyt, P. and and Bulow, R. and Cardenas-Jaen, K. and Cortegoso, P. and Fontana, M. and and Haeberle, L. and Heckler, M. and Litvin, A. and Mann, K. and and Michalski, C. and Michl, P. and Nappo, G. and Perri, G. and Persson, S. and and Scheufele, F. and Sclafani, F. and Schmidt, M. and Venezia, L. and and Volker, F. and Vullierm, M-P and Wusten, L. and European Study Grp and Cystic Tum",
    journal = "Gut Pathogens",
    year = "2018",
    volume = "67",
    number = "5",
    pages = "789-804",
    publisher = "BMJ Publishing Group",
    issn = "1757-4749",
    doi = "10.1136/gutjnl-2018-316027",
    abstract = "Evidence-based guidelines on the management of pancreatic cystic
neoplasms (PCN) are lacking. This guideline is a joint initiative of the
European Study Group on Cystic Tumours of the Pancreas, United European
Gastroenterology, European Pancreatic Club, European-African
Hepato-Pancreato-Biliary Association, European Digestive Surgery, and
the European Society of Gastrointestinal Endoscopy. It replaces the 2013
European consensus statement guidelines on PCN. European and
non-European experts performed systematic reviews and used GRADE
methodology to answer relevant clinical questions on nine topics
(biomarkers, radiology, endoscopy, intraductal papillary mucinous
neoplasm (IPMN), mucinous cystic neoplasm (MCN), serous cystic neoplasm,
rare cysts, (neo)adjuvant treatment, and pathology). Recommendations
include conservative management, relative and absolute indications for
surgery. A conservative approach is recommended for asymptomatic MCN and
IPMN measuring < 40 mm without an enhancing nodule. Relative indications
for surgery in IPMN include a main pancreatic duct (MPD) diameter
between 5 and 9.9 mm or a cyst diameter >= 40 mm. Absolute indications
for surgery in IPMN, due to the high-risk of malignant transformation,
include jaundice, an enhancing mural nodule > 5 mm, and MPD diameter >
10 mm. Lifelong follow-up of IPMN is recommended in patients who are fit
for surgery. The European evidence-based guidelines on PCN aim to
improve the diagnosis and management of PCN."
}