@article{3180839, title = "Primary Ewing sarcoma of the axis-C2: A case report and the review of the literature", author = "Paraskeva, Kyriakos and Giakoumettis, Dimitrios and Nikas, Ioannis and and Georgoulis, George and Sfakianos, George and Themistocleous, Marios S.", journal = "Neurologia I Neurochirurgia Polska / Polish Journal of Neurology and Neurosurgery", year = "2018", volume = "52", number = "4", pages = "534-542", publisher = "Via Medica SP Zoo", issn = "0028-3843", doi = "10.1016/j.pjnns.2018.02.005", keywords = "Neuroectodermal; Malignancy; Atlantoaxial; Torticollis; Ewing's sarcoma", abstract = "Introduction: Neck pain and torticollis are common symptoms in the pediatric population that rarely requires further investigation. However, in case symptoms persist, then a more meticulously approach should be considered. Underlying conditions such as infections, neck injury, autoimmune disorders or even cervical spine cancer should be excluded from diagnosis. Cervical spine cancer is a rare neurosurgical entity in the pediatric population and even rarer is atlantoaxial Ewing's sarcoma. In this report, we present a rare case of primary Ewing's sarcoma of the axis. Case report: A 3.5-year-old female with progressive neck pain and intermittent episodes of torticollis was referred to our outpatient clinic. Imaging studies revealed a malignant tumor located on C2 vertebra. Diagnosis of Ewing's Sarcomawas confirmed via open biopsy and the patient was treated with Euro-EWING 99 chemotherapy. Conclusion: Pediatric neck pain and/or torticollis should raise high suspicion for malignancy of cervical spine. Modern diagnostic means and techniques can assist in the screening and diagnosis of these tumors. (C) 2018 Polish Neurological Society. Published by Elsevier Sp. z o. o. All rights reserved." }