@article{3182027, title = "Systemic lupus erythematosus: state of the art on clinical practice guidelines", author = "Tamirou, Farah and Arnaud, Laurent and Talarico, Rosaria and Scire, and Carlo Alberto and Alexander, Tobias and Amoura, Zahir and Avcin, Tadej and and Bortoluzzi, Alessandra and Cervera, Ricard and Conti, Fabrizio and and Cornet, Alain and Devilliers, Herve and Doria, Andrea and Frassi, Micol and and Fredi, Micaela and Govoni, Marcello and Houssiau, Frederic and and Llado, Ana and Macieira, Carla and Martin, Thierry and Massaro, Laura and and Moraes-Fontes, Maria Francisca and Pamfil, Cristina and Paolino, and Sabrina and Tani, Chiara and Tas, Sander W. and Tektonidou, Maria and and Tincani, Angela and Van Vollenhoven, Ronald F. and Bombardieri, Stefano and and Burmester, Gerd and Fonseca, Joao Eurico and Galetti, Ilaria and and Hachulla, Eric and Mueller-Ladner, Ulf and Schneider, Matthias and and Smith, Vanessa and Cutolo, Maurizio and Mosca, Marta and and Costedoat-Chalumeau, Nathalie", journal = "RMD Open: Rheumatic & Musculoskeletal Diseases", year = "2018", volume = "4", number = "1", publisher = "BMJ Publishing Group", issn = "2056-5933", doi = "10.1136/rmdopen-2018-000793", abstract = "Systemic lupus erythematosus (SLE) is the paradigm of systemic autoimmune diseases characterised by a wide spectrum of clinical manifestations with an unpredictable relapsing-remitting course. The aim of the present work was to identify current available clinical practice guidelines (CPGs) for SLE, to provide their review and to identify physicians' and patients' unmet needs. Twenty-three original guidelines published between 2004 and 2017 were identified. Many aspects of disease management are covered, including global disease management, lupus nephritis and neuropsychiatric involvement, management of pregnancies, vaccinations and comorbidities monitoring. Unmet needs relate with disease management of some clinical manifestations and adherence to treatment. Many patient's unmet needs have been identified starting with faster diagnosis, need for more therapeutic options, guidelines on lifestyle issues, attention to quality of life and adequate education." }