@article{3189000,
    title = "A novel approach regarding the anti-aging of facial skin through
collagen reorganization",
    author = "Sifaki, Maria and Calina, Daniela and Docea, Anca Oana and Tsioumas, and Sotiris and Katsarou, Martha-Spyridoula and Papadogiorgaki, Sevasti and and Fragkiadaki, Persefoni and Branisteanu, Daciana Elena and Kouskoukis, and Konstantinos and Tsiaoussis, John and Spandidos, Demetrios A.",
    journal = "Experimental and Therapeutic Medicine",
    year = "2020",
    volume = "19",
    number = "1",
    pages = "717-721",
    publisher = "SPANDIDOS PUBL LTD",
    issn = "1792-0981, 1792-1015",
    doi = "10.3892/etm.2019.8254",
    keywords = "collagen reorganization; anti-aging effect; needle shaping; facial skin;
new collagen synthesis",
    abstract = "The needle shaping technique can be used to perform subcutaneous
microtransplants, enabling the ‘lifting’ of the skin. This prospective
cohort study aimed to examine the effects of needle shaping on facial
skin tone, volume and histological structure. A total of 54 women
underwent the needle shaping procedure performed by inserting a tiny
acupuncture needle combined with mixed electrical currents. The overall
treatment was completed within 4 sessions of 2 months apart, once every
15 days. Maintenance was ensured by 2 sessions (no longer than 15 days
apart) every 6 months. Macroscopic skin appearance was evaluated by a
specialized dermatologist and the satisfaction of the patients was
assessed. The microscopic structure of the skin dermis was evaluated by
optic and scanning electron microscopy. I-chrome staining demonstrated
more compact dermis-collagen fibers which were larger and thicker as
compared to the controls. Scanning electron microscopy demonstrated an
increased dermis thickness as compared to pre-treatment. All patients
that answered to the follow up reported satisfaction during assessment.
The satisfaction of the patients was very good and excellent in 45% of
cases. The results of the needle-shaping procedure are natural with no
scaring or down time. Moreover, the result is lasting even for 1 year,
depending always on the subject’s lifestyle and general health
condition."
}