@article{3191176, title = "COVID-19 and Thrombotic or Thromboembolic Disease: Implications for Prevention, Antithrombotic Therapy, and Follow", author = "Bikdeli, Behnood and Madhavan, Mahesh V. and Jimenez, David and Chuich, and Taylor and Dreyfus, Isaac and Driggin, Elissa and Der Nigoghossian, and Caroline and Ageno, Walter and Madjid, Mohammad and Guo, Yutao and Tang, and Liang V. and Hu, Yu and Giri, Jay and Cushman, Mary and Quere, Isabelle and and Dimakakos, Evangelos P. and Gibson, C. Michael and Lippi, Giuseppe and and Favaloro, Emmanuel J. and Fareed, Jawed and Caprini, Joseph A. and and Tafur, Alfonso J. and Burton, John R. and Francese, Dominic P. and Wang, and Elizabeth Y. and Falanga, Anna and McLintock, Claire and Hunt, Beverley and J. and Spyropoulos, Alex C. and Barnes, Geoffrey D. and Eikelboom, John and W. and Weinberg, Ido and Schulman, Sam and Carrier, Marc and Piazza, and Gregory and Beckman, Joshua A. and Steg, Gabriel and Stone, Gregg W. and and Rosenkranz, Stephan and Goldhaber, Samuel Z. and Parikh, Sahil A. and and Monreal, Manuel and Krumholz, Harlan M. and Konstantinides, Stavros V. and and Weitz, Jeffrey I. and Lip, Gregory Y. H. and Global COVID-19 and Thrombosis Collabo and ISTH and NATF and ESVM and ESC Working Grp Pulm and Ci", journal = "Journal of the American College of Cardiology", year = "2020", volume = "75", number = "23", pages = "2950-2973", publisher = "EXCERPTA MEDICA INC-ELSEVIER SCIENCE INC", issn = "0735-1097, 1558-3597", doi = "10.1016/j.jacc.2020.04.031", abstract = "Coronavirus disease-2019 (COVID-19), a viral respiratory illness caused by the severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2), may predispose patients to thrombotic disease, both in the venous and arterial circulations, because of excessive inflammation, platelet activation, endothelial dysfunction, and stasis. In addition, many patients receiving antithrombotic therapy for thrombotic disease may develop COVID-19, which can have implications for choice, dosing, and laboratory monitoring of antithrombotic therapy. Moreover, during a time with much focus on COVID-19, it is critical to consider how to optimize the available technology to care for patients without COVID-19 who have thrombotic disease. Herein, the authors review the current understanding of the pathogenesis, epidemiology, management, and outcomes of patients with COVID-19 who develop venous or arterial thrombosis, of those with pre-existing thrombotic disease who develop COVID-19, or those who need prevention or care for their thrombotic disease during the COVID-19 pandemic. (J Am Coll Cardiol 2020;75:2950-73) (c) 2020 by the American College of Cardiology Foundation." }