@article{3200225,
    title = "Parental Occupational Exposures and Risk of Childhood Acute Leukemia.",
    author = "Kyriakopoulou, Aleka and Meimeti, Evangelia and Moisoglou, Ioannis and Psarrou, Anna and Provatopoulou, Xeni and Dounias, Georgios",
    journal = "Materia socio-medica",
    year = "2018",
    volume = "30",
    number = "3",
    pages = "209--214",
    doi = "10.5455/msm.2018.30.209-214",
    keywords = "Childhood acute leukemia, electromagnetic fields, harmful chemicals, occupational exposures, risk factors, social contacts",
    abstract = "INTRODUCTION: Acute leukemia, accounting for 20% of all cancers diagnosed in individuals younger than 19 years old, is the most prevalent childhood malignancy.  Among environmental risk factors, parental occupational exposures have attracted  scientific interest as potential predisposing factors for childhood leukemia. The  role of parental occupational exposure to social contacts, harmful chemicals,  electromagnetic fields and ionizing radiation has been investigated with conflicting  and inconsistent results. AIM: A case-control study aiming to assess the association  between parental occupational exposures to social contacts, chemicals and  electromagnetic fields and the risk of offspring acute leukemia. MATERIAL AND  METHODS: 108 children with acute leukemia and equal number of matched controls were  included. Data on parental occupations before conception, during pregnancy, during  breastfeeding and after birth, and on potential risk factors was recorded.  Associations between parental exposure and risk of childhood leukemia were  estimated. RESULTS: Parental occupational exposure during the four periods of  exposure was not associated with childhood leukemia. High birth weight and family  history of cancer were associated with the development of childhood acute leukemia.  A weak association of maternal medication use during pregnancy and leukemia risk  emerged. CONCLUSIONS: Since the causative factors of childhood leukemia remain  unknown, further investigation is mandatory for the reduction of disease burden."
}