@article{3219343,
    title = "Oncoplastic breast consortium recommendations for mastectomy and whole breast reconstruction in the setting of post-mastectomy radiation therapy",
    author = "Weber, W.P. and Shaw, J. and Pusic, A. and Wyld, L. and Morrow, M. and King, T. and Mátrai, Z. and Heil, J. and Fitzal, F. and Potter, S. and Rubio, I.T. and Cardoso, M.-J. and Gentilini, O.D. and Galimberti, V. and Sacchini, V. and Rutgers, E.J.T. and Benson, J. and Allweis, T.M. and Haug, M. and Paulinelli, R.R. and Kovacs, T. and Harder, Y. and Gulluoglu, B.M. and Gonzalez, E. and Faridi, A. and Elder, E. and Dubsky, P. and Blohmer, J.-U. and Bjelic-Radisic, V. and Barry, M. and Hay, S.D. and Bowles, K. and French, J. and Reitsamer, R. and Koller, R. and Schrenk, P. and Kauer-Dorner, D. and Biazus, J. and Brenelli, F. and Letzkus, J. and Saccilotto, R. and Joukainen, S. and Kauhanen, S. and Karhunen-Enckell, U. and Hoffmann, J. and Kneser, U. and Kühn, T. and Kontos, M. and Tampaki, E.C. and Carmon, M. and Hadar, T. and Catanuto, G. and Garcia-Etienne, C.A. and Koppert, L. and Gouveia, P.F. and Lagergren, J. and Svensjö, T. and Maggi, N. and Kappos, E.A. and Schwab, F.D. and Castrezana, L. and Steffens, D. and Krol, J. and Tausch, C. and Günthert, A. and Knauer, M. and Katapodi, M.C. and Bucher, S. and Hauser, N. and Kurzeder, C. and Mucklow, R. and Tsoutsou, P.G. and Sezer, A. and Çakmak, G.K. and Karanlik, H. and Fairbrother, P. and Romics, L. and Montagna, G. and Urban, C. and Walker, M. and Formenti, S.C. and Gruber, G. and Zimmermann, F. and Zwahlen, D.R. and Kuemmel, S. and El-Tamer, M. and Vrancken Peeters, M.J. and Kaidar-Person, O. and Gnant, M. and Poortmans, P. and de Boniface, J.",
    journal = "Gastric and Breast Cancer",
    year = "2022",
    volume = "63",
    pages = "123-139",
    publisher = "Churchill Livingstone",
    doi = "10.1016/j.breast.2022.03.008",
    keywords = "breast reconstruction;  breast tumor;  female;  human;  mastectomy;  nipple;  procedures;  prospective study, Breast Neoplasms;  Female;  Humans;  Mammaplasty;  Mastectomy;  Nipples;  Prospective Studies",
    abstract = "Aim: Demand for nipple- and skin- sparing mastectomy (NSM/SSM) with immediate breast reconstruction (BR) has increased at the same time as indications for post-mastectomy radiation therapy (PMRT) have broadened. The aim of the Oncoplastic Breast Consortium initiative was to address relevant questions arising with this clinically challenging scenario. Methods: A large global panel of oncologic, oncoplastic and reconstructive breast surgeons, patient advocates and radiation oncologists developed recommendations for clinical practice in an iterative process based on the principles of Delphi methodology. Results: The panel agreed that surgical technique for NSM/SSM should not be formally modified when PMRT is planned with preference for autologous over implant-based BR due to lower risk of long-term complications and support for immediate and delayed-immediate reconstructive approaches. Nevertheless, it was strongly believed that PMRT is not an absolute contraindication for implant-based or other types of BR, but no specific recommendations regarding implant positioning, use of mesh or timing were made due to absence of high-quality evidence. The panel endorsed use of patient-reported outcomes in clinical practice. It was acknowledged that the shape and size of reconstructed breasts can hinder radiotherapy planning and attention to details of PMRT techniques is important in determining aesthetic outcomes after immediate BR. Conclusions: The panel endorsed the need for prospective, ideally randomised phase III studies and for surgical and radiation oncology teams to work together for determination of optimal sequencing and techniques for PMRT for each patient in the context of BR © 2022 The Authors"
}