@article{3219718,
    title = "A Combination of Mediterranean and Low-FODMAP Diets for Managing IBS Symptoms? Ask Your Gut!",
    author = "Kasti, A. and Petsis, K. and Lambrinou, S. and Katsas, K. and Nikolaki, M. and Papanikolaou, I.S. and Hatziagelaki, E. and Triantafyllou, K.",
    journal = "Microorganisms",
    year = "2022",
    volume = "10",
    number = "4",
    publisher = "MDPI",
    doi = "10.3390/microorganisms10040751",
    abstract = "Among other factors, food intolerance is cardinal in triggering irritable bowel syndrome (IBS) symptoms in a significant percentage of patients. As a result, specific dietary patterns are the first-line therapeutic approach. The low-FODMAP diet (LFD) is gaining ground as the most welldocumented diet intervention that significantly reduces IBS symptoms. Though the LFD improves symptoms, the diet’s impact on intestinal low-grade inflammation, one of the cardinal mechanisms contributing to symptom development, remains doubtful. On the other hand, the Mediterranean diet (MedDiet) is recommended for chronic low-grade inflammation-related diseases because of its anti-inflammatory properties, derived predominantly from olive oil and phenolic compounds. Thus far, the role of a modified LFD, enriched with the MedDiet’s anti-inflammatory components, has not been evaluated in IBS patients. This review aims to examine the hypothesis of a potential combination of the immunomodulatory effects of the MedDiet with the LFD to improve IBS symptoms. © 2022 by the authors. Licensee MDPI, Basel, Switzerland."
}