@article{3220695,
    title = "Tea consumption and gastric cancer: a pooled analysis from the Stomach cancer Pooling (StoP) Project consortium",
    author = "Martimianaki, G. and Alicandro, G. and Pelucchi, C. and Bonzi, R. and Rota, M. and Hu, J. and Johnson, K.C. and Rabkin, C.S. and Liao, L.M. and Sinha, R. and Zhang, Z.-F. and Dalmartello, M. and Lunet, N. and Morais, S. and Palli, D. and Ferraroni, M. and Yu, G.-P. and Tsugane, S. and Hidaka, A. and Curado, M.P. and Dias-Neto, E. and Zaridze, D. and Maximovitch, D. and Vioque, J. and Garcia de la Hera, M. and López-Carrillo, L. and Hernández-Ramírez, R.U. and Hamada, G.S. and Ward, M.H. and Mu, L. and Malekzadeh, R. and Pourfarzi, F. and Trichopoulou, A. and Karakatsani, A. and Kurtz, R.C. and Lagiou, A. and Lagiou, P. and Boccia, S. and Boffetta, P. and Camargo, M.C. and Negri, E. and La Vecchia, C.",
    journal = "British Journal of Cancer",
    year = "2022",
    publisher = "Springer Nature BV",
    issn = "0007-0920, 1532-1827",
    doi = "10.1038/s41416-022-01856-w",
    abstract = "Background: Evidence from epidemiological studies on the role of tea drinking in gastric cancer risk remains inconsistent. We aimed to investigate and quantify the relationship between tea consumption and gastric cancer in the Stomach cancer Pooling (StoP) Project consortium. Methods: A total of 9438 cases and 20,451 controls from 22 studies worldwide were included. Odds ratios (ORs) and the corresponding 95% confidence intervals (CIs) of gastric cancer for regular versus non-regular tea drinkers were estimated by one and two-stage modelling analyses, including terms for sex, age and the main recognised risk factors for gastric cancer. Results: Compared to non-regular drinkers, the estimated adjusted pooled OR for regular tea drinkers was 0.91 (95% CI: 0.85–0.97). When the amount of tea consumed was considered, the OR for consumption of 1–2 cups/day was 1.01 (95% CI: 0.94–1.09) and for >3 cups/day was 0.91 (95% CI: 0.80–1.03). Stronger inverse associations emerged among regular drinkers in China and Japan (OR: 0.67, 95% CI: 0.49–0.91) where green tea is consumed, in subjects with H. pylori infection (OR: 0.68, 95% CI: 0.58–0.80), and for gastric cardia cancer (OR: 0.64, 95% CI: 0.49–0.84). Conclusion: Our results indicate a weak inverse association between tea consumption and gastric cancer. © 2022, The Author(s), under exclusive licence to Springer Nature Limited."
}