@article{3220971,
    title = "Risk factors for head and neck cancer in more and less developed countries: Analysis from the INHANCE consortium",
    author = "Goyal, N. and Hennessy, M. and Lehman, E. and Lin, W. and Agudo, A. and Ahrens, W. and Boccia, S. and Brennan, P. and Brenner, H. and Cadoni, G. and Canova, C. and Chen, C. and Conway, D. and Curado, M. and Dal Maso, L. and Daudt, A.W. and Edefonti, V. and Fabianova, E. and Fernandez, L. and Franceschi, S. and Garavello, W. and Gillison, M. and Hayes, R.B. and Healy, C. and Herrero, R. and Holcatova, I. and Kanda, J.L. and Kelsey, K. and Hansen, B. and Koifman, R. and Lagiou, P. and La Vecchia, C. and Levi, F. and Li, G. and Lissowska, J. and Mendoza López, R. and Luce, D. and Macfarlane, G. and Mates, D. and Matsuo, K. and McClean, M. and Menezes, A. and Menvielle, G. and Morgenstern, H. and Moysich, K. and Negri, E. and Olshan, A.F. and Pandics, T. and Polesel, J. and Purdue, M. and Radoi, L. and Ramroth, H. and Richiardi, L. and Schantz, S. and Schwartz, S.M. and Serraino, D. and Shangina, O. and Smith, E. and Sturgis, E.M. and Świątkowska, B. and Thomson, P. and Vaughan, T.L. and Vilensky, M. and Winn, D.M. and Wunsch-Filho, V. and Yu, G.-P. and Zevallos, J.P. and Zhang, Z.-F. and Zheng, T. and Znaor, A. and Boffetta, P. and Hashibe, M. and Lee, Y.-C.A. and Muscat, J.E.",
    journal = "Journal of Oral Diseases",
    year = "2022",
    publisher = "John Wiley and Sons Inc",
    issn = "2314-6516",
    doi = "10.1111/odi.14196",
    abstract = "Objective: We analyzed the pooled case-control data from the International Head and Neck Cancer Epidemiology (INHANCE) consortium to compare cigarette smoking and alcohol consumption risk factors for head and neck cancer between less developed and more developed countries. Subjects and Methods: The location of each study was categorized as either a less developed or more developed country. We compared the risk of overall head and neck cancer and cancer of specific anatomic subsites associated with cigarette smoking and alcohol consumption. Additionally, age and sex distribution between categories was compared. Results: The odds ratios for head and neck cancer sites associated with smoking duration differed between less developed and more developed countries. Smoking greater than 20 years conferred a higher risk for oral cavity and laryngeal cancer in more developed countries, whereas the risk was greater for oropharynx and hypopharynx cancer in less developed countries. Alcohol consumed for more than 20 years conferred a higher risk for oropharynx, hypopharynx, and larynx cancer in less developed countries. The proportion of cases that were young (<45 years) or female differed by country type for some HNC subsites. Conclusion: These findings suggest the degree of industrialization and economic development affects the relationship between smoking and alcohol with head and neck cancer. © 2022 Wiley Periodicals LLC."
}