TY - JOUR
TI - Depression prevalence using the HADS-D compared to SCID major depression classification: An individual participant data meta-analysis
AU - Brehaut, E.
AU - Neupane, D.
AU - Levis, B.
AU - Wu, Y.
AU - Sun, Y.
AU - Krishnan, A.
AU - He, C.
AU - Bhandari, P.M.
AU - Negeri, Z.
AU - Riehm, K.E.
AU - Rice, D.B.
AU - Azar, M.
AU - Yan, X.W.
AU - Imran, M.
AU - Chiovitti, M.J.
AU - Saadat, N.
AU - Cuijpers, P.
AU - Ioannidis, J.P.A.
AU - Markham, S.
AU - Patten, S.B.
AU - Ziegelstein, R.C.
AU - Henry, M.
AU - Ismail, Z.
AU - Loiselle, C.G.
AU - Mitchell, N.D.
AU - Tonelli, M.
AU - Boruff, J.T.
AU - Kloda, L.A.
AU - Beraldi, A.
AU - Braeken, A.P.B.M.
AU - Carter, G.
AU - Clover, K.
AU - Conroy, R.M.
AU - Cukor, D.
AU - da Rocha e Silva, C.E.
AU - De Souza, J.
AU - Downing, M.G.
AU - Feinstein, A.
AU - Ferentinos, P.P.
AU - Fischer, F.H.
AU - Flint, A.J.
AU - Fujimori, M.
AU - Gallagher, P.
AU - Goebel, S.
AU - Jetté, N.
AU - Julião, M.
AU - Keller, M.
AU - Kjærgaard, M.
AU - Love, A.W.
AU - Löwe, B.
AU - Martin-Santos, R.
AU - Michopoulos, I.
AU - Navines, R.
AU - O'Rourke, S.J.
AU - Öztürk, A.
AU - Pintor, L.
AU - Ponsford, J.L.
AU - Rooney, A.G.
AU - Sánchez-González, R.
AU - Schwarzbold, M.L.
AU - Sharpe, M.
AU - Simard, S.
AU - Singer, S.
AU - Stone, J.
AU - Tung, K.-Y.
AU - Turner, A.
AU - Walker, J.
AU - Walterfang, M.
AU - White, J.
AU - Benedetti, A.
AU - Thombs, B.D.
JO - Journal of Psychosomatic Research
PY - 2020
VL - 139
TODO - null
SP - null
PB - ELSEVIER SCIENCE INC 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA
SN - 0022-3999
TODO - 10.1016/j.jpsychores.2020.110256
TODO - Article;  confidence interval;  diagnostic accuracy;  disease classification;  Hospital Anxiety and Depression Scale;  human;  major depression;  meta analysis;  patient information;  predictive value;  prevalence;  Structured Clinical Interview for DSM Disorders;  systematic review;  adult;  aged;  classification;  depression;  female;  major depression;  male;  middle aged, Adult;  Aged;  Depression;  Depressive Disorder, Major;  Female;  Humans;  Male;  Middle Aged;  Prevalence
TODO - Objectives: Validated diagnostic interviews are required to classify depression status and estimate prevalence of disorder, but screening tools are often used instead. We used individual participant data meta-analysis to compare prevalence based on standard Hospital Anxiety and Depression Scale – depression subscale (HADS-D) cutoffs of ≥8 and ≥11 versus Structured Clinical Interview for DSM (SCID) major depression and determined if an alternative HADS-D cutoff could more accurately estimate prevalence. Methods: We searched Medline, Medline In-Process & Other Non-Indexed Citations via Ovid, PsycINFO, and Web of Science (inception-July 11, 2016) for studies comparing HADS-D scores to SCID major depression status. Pooled prevalence and pooled differences in prevalence for HADS-D cutoffs versus SCID major depression were estimated. Results: 6005 participants (689 SCID major depression cases) from 41 primary studies were included. Pooled prevalence was 24.5% (95% Confidence Interval (CI): 20.5%, 29.0%) for HADS-D ≥8, 10.7% (95% CI: 8.3%, 13.8%) for HADS-D ≥11, and 11.6% (95% CI: 9.2%, 14.6%) for SCID major depression. HADS-D ≥11 was closest to SCID major depression prevalence, but the 95% prediction interval for the difference that could be expected for HADS-D ≥11 versus SCID in a new study was −21.1% to 19.5%. Conclusions: HADS-D ≥8 substantially overestimates depression prevalence. Of all possible cutoff thresholds, HADS-D ≥11 was closest to the SCID, but there was substantial heterogeneity in the difference between HADS-D ≥11 and SCID-based estimates. HADS-D should not be used as a substitute for a validated diagnostic interview. © 2020 Elsevier Inc.
ER -