TY - JOUR TI - A Holographic Augmented Reality Interface for Visualizing of MRI Data and Planning of Neurosurgical Procedures AU - Morales Mojica, C.M. AU - Velazco-Garcia, J.D. AU - Pappas, E.P. AU - Birbilis, T.A. AU - Becker, A. AU - Leiss, E.L. AU - Webb, A. AU - Seimenis, I. AU - Tsekos, N.V. JO - Journal of Digital Imaging PY - 2021 VL - 34 TODO - 4 SP - 1014-1025 PB - Springer Science and Business Media Deutschland GmbH SN - 0897-1889, 1618-727X TODO - 10.1007/s10278-020-00412-3 TODO - Augmented reality; Data visualization; Helmet mounted displays; Holography; Image enhancement; Three dimensional computer graphics; Visualization, Anatomical structures; Brain vasculature; Computational loads; Computational platforms; Forbidden region; Head mounted displays; Qualitative evaluations; Segmented structure, Magnetic resonance imaging, computer assisted surgery; computer interface; holography; neurosurgery; nuclear magnetic resonance imaging; software; three-dimensional imaging, Augmented Reality; Holography; Imaging, Three-Dimensional; Magnetic Resonance Imaging; Neurosurgical Procedures; Software; Surgery, Computer-Assisted; User-Computer Interface TODO - The recent introduction of wireless head-mounted displays (HMD) promises to enhance 3D image visualization by immersing the user into 3D morphology. This work introduces a prototype holographic augmented reality (HAR) interface for the 3D visualization of magnetic resonance imaging (MRI) data for the purpose of planning neurosurgical procedures. The computational platform generates a HAR scene that fuses pre-operative MRI sets, segmented anatomical structures, and a tubular tool for planning an access path to the targeted pathology. The operator can manipulate the presented images and segmented structures and perform path-planning using voice and gestures. On-the-fly, the software uses defined forbidden-regions to prevent the operator from harming vital structures. In silico studies using the platform with a HoloLens HMD assessed its functionality and the computational load and memory for different tasks. A preliminary qualitative evaluation revealed that holographic visualization of high-resolution 3D MRI data offers an intuitive and interactive perspective of the complex brain vasculature and anatomical structures. This initial work suggests that immersive experiences may be an unparalleled tool for planning neurosurgical procedures. © 2021, Society for Imaging Informatics in Medicine. ER -