TY - JOUR
TI - Does route of full feeding affect outcome among ventilated critically ill covid-19 patients: A prospective observational study
AU - Karayiannis, D.
AU - Kakavas, S.
AU - Sarri, A.
AU - Giannopoulou, V.
AU - Liakopoulou, C.
AU - Jahaj, E.
AU - Kanavou, A.
AU - Pitsolis, T.
AU - Malachias, S.
AU - Adamos, G.
AU - Mantelou, A.
AU - Almperti, A.
AU - Morogianni, K.
AU - Kampouropoulou, O.
AU - Kotanidou, A.
AU - Mastora, Z.
JO - Nutrient Cycling in Agroecosystems
PY - 2022
VL - 14
TODO - 1
SP - null
PB - MDPI
SN - 1385-1314
TODO - 10.3390/nu14010153
TODO - artificial ventilation;  critical illness;  enteric feeding;  epidemiology;  female;  Greece;  human;  intensive care;  length of stay;  male;  middle aged;  mortality;  parenteral nutrition;  procedures;  prospective study;  therapy;  time factor;  treatment outcome, COVID-19;  Critical Care;  Critical Illness;  Enteral Nutrition;  Female;  Greece;  Humans;  Length of Stay;  Male;  Middle Aged;  Parenteral Nutrition;  Prospective Studies;  Respiration, Artificial;  SARS-CoV-2;  Time Factors;  Treatment Outcome
TODO - The outbreak of the new coronavirus strain SARS-CoV-2 (COVID-19) highlighted the need for appropriate feeding practices among critically ill patients admitted to the intensive care unit (ICU). This study aimed to describe feeding practices of intubated COVID-19 patients during their second week of hospitalization in the First Department of Critical Care Medicine, Evaggelismos General Hospital, and evaluate potential associations with all cause 30-day mortality, length of hospital stay, and duration of mechanical ventilation. We enrolled adult intubated COVID-19 patients admitted to the ICU between September 2020 and July 2021 and prospectively monitored until their hospital discharge. Of the 162 patients analyzed (52.8% men, 51.6% overweight/obese, mean age 63.2 ± 1.9 years), 27.2% of patients used parenteral nutrition, while the rest were fed enterally. By 30 days, 34.2% of the patients in the parenteral group had died compared to 32.7% of the patients in the enteral group (relative risk (RR) for the group receiving enteral nutrition = 0.97, 95% confidence interval = 0.88–1.06, p = 0.120). Those in the enteral group demonstrated a lower duration of hospital stay (RR = 0.91, 95% CI = 0.85-0.97, p = 0.036) as well as mechanical ventilation support (RR = 0.94, 95% CI = 0.89–0.99, p = 0.043). Enteral feeding during second week of ICU hospitalization may be associated with a shorter duration of hospitalization and stay in mechanical ventilation support among critically ill intubated patients with COVID-19. © 2021 by the authors. Licensee MDPI, Basel, Switzerland.
ER -