TY - JOUR
TI - The significant role of carnitine and fatty acids during pregnancy, lactation and perinatal period. Nutritional support in specific groups of pregnant women
AU - Manta-Vogli, P.D.
AU - Schulpis, K.H.
AU - Dotsikas, Y.
AU - Loukas, Y.L.
JO - Clinical Nutrition Open Science
PY - 2020
VL - 39
TODO - 8
SP - 2337-2346
PB - Churchill Livingstone
SN - null
TODO - 10.1016/j.clnu.2019.10.025
TODO - carnitine;  fatty acid;  polyunsaturated fatty acid;  saturated fatty acid;  trans fatty acid;  carnitine;  fatty acid, birth weight;  blood level;  fat intake;  fatty acid blood level;  fetus development;  human;  lactation;  maternal nutrition;  maternal obesity;  metabolism;  nutritional support;  perinatal period;  pregnancy;  pregnancy diabetes mellitus;  pregnancy outcome;  pregnant woman;  Review;  social status;  total parenteral nutrition;  vegetarian diet;  administration and dosage;  adult;  blood;  diet therapy;  dietary supplement;  female;  lactation;  maternal nutrition;  pregnancy;  prenatal care;  procedures, Adult;  Carnitine;  Dietary Fats;  Dietary Supplements;  Fatty Acids;  Female;  Humans;  Lactation;  Maternal Nutritional Physiological Phenomena;  Nutrition Therapy;  Pregnancy;  Prenatal Care
TODO - Background & aims: Pregnancy is characterized by a complexity of metabolic processes that may impact fetal health and development. Women's nutrition during pregnancy and lactation is considered important for both mother and infant. This review aims to investigate the significant role of fatty acids and carnitine during pregnancy and lactation in specific groups of pregnant and lactating women. Methods: The literature was reviewed using relevant data bases (e.g. Pubmed, Scopus, Science Direct) and relevant articles were selected to provide information and data for the text and associated Tables. Results: Dynamic features especially of plasma carnitine profile during pregnancy and lactation, indicate an extraordinarily active participation of carnitine in the intermediary metabolism both in pregnant woman and in neonate and may also have implications for health and disease later in life. Maternal diets rich in trans and saturated fatty acids can lead to impairments in the metabolism and development of the offspring, whereas the consumption of long chain-polyunsaturated fatty acids during pregnancy plays a beneficial physiologic and metabolic role in the health of offspring. Conclusions: Pregnant women who are underweight, overweight or obese, with gestational diabetes mellitus or diabetes mellitus and those who choose vegan/vegetarian diets or are coming from socially disadvantaged areas, should be nutritionally supported to achieve a higher quality diet during pregnancy and/or lactation. © 2019 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism
ER -